Premature ovarian insufficiency: a review on the role of oxidative stress and the application of antioxidants
YQ Shi, XT Zhu, SN Zhang, YF Ma, YH Han… - Frontiers in …, 2023 - frontiersin.org
Normal levels of reactive oxygen species (ROS) play an important role in regulating follicular
growth, angiogenesis and sex hormone synthesis in ovarian tissue. When the balance …
growth, angiogenesis and sex hormone synthesis in ovarian tissue. When the balance …
Role of the Nrf2 Signaling Pathway in Ovarian Aging: Potential Mechanism and Protective Strategies
X Gao, B Wang, Y Huang, M Wu, Y Li, Y Li… - International Journal of …, 2023 - mdpi.com
The ovary holds a significant role as a reproductive endocrine organ in women, and its
aging process bears implications such as menopause, decreased fertility, and long-term …
aging process bears implications such as menopause, decreased fertility, and long-term …
Diminished Ovarian Reserve in Endometriosis: Insights from In Vitro, In Vivo, and Human Studies—A Systematic Review
Z Tan, X Gong, CC Wang, T Zhang… - International Journal of …, 2023 - mdpi.com
Endometriosis, a prevalent disorder in women of reproductive age, is often associated with
undesired infertility. Ovarian reserve, an essential measure of ovarian function that is crucial …
undesired infertility. Ovarian reserve, an essential measure of ovarian function that is crucial …
Pyridoxamine protects human granulosa cells against advanced glycation end-products-induced steroidogenesis disturbances
M Mirani, S Bahmanpour, F Masjedi… - Molecular Biology …, 2023 - Springer
Background Ovarian advanced glycation end-products (AGEs) accumulation is associated
with ovarian granulosa cells (GCs) dysfunction. Vitamin B6 derivatives positively affected …
with ovarian granulosa cells (GCs) dysfunction. Vitamin B6 derivatives positively affected …
Integration of multi-modal datasets to estimate human aging
Aging involves complex biological processes leading to the decline of living organisms. As
population lifespan increases worldwide, the importance of identifying factors underlying …
population lifespan increases worldwide, the importance of identifying factors underlying …
Dynamics of serum exosome microRNA profile altered by chemically induced estropause and rescued by estrogen therapy in female mice
BM Zanini, BM de Avila, DN Garcia, JD Hense… - GeroScience, 2024 - Springer
The decline in the ovarian reserve leads to menopause and reduced serum estrogens.
MicroRNAs are small non-coding RNAs, which can regulate gene expression and be …
MicroRNAs are small non-coding RNAs, which can regulate gene expression and be …
[HTML][HTML] Targeting organ-specific mitochondrial dysfunction to improve biological aging
CT Madreiter-Sokolowski, U Hiden, J Krstic… - Pharmacology & …, 2024 - Elsevier
In an aging society, unveiling new anti-aging strategies to prevent and combat aging-related
diseases is of utmost importance. Mitochondria are the primary ATP production sites and key …
diseases is of utmost importance. Mitochondria are the primary ATP production sites and key …
Understanding the mechanisms of diminished Ovarian Reserve: insights from genetic variants and Regulatory factors
Q Zhu, H Ma, J Wang, X Liang - Reproductive Sciences, 2024 - Springer
Delaying childbearing age has become a trend in modern times, but it has also led to a
common challenge in clinical reproductive medicine—diminished ovarian reserve (DOR) …
common challenge in clinical reproductive medicine—diminished ovarian reserve (DOR) …
[HTML][HTML] Autophagy and Female Fertility: Mechanisms, Clinical Implications, and Emerging Therapies
Autophagy, an evolutionarily conserved cellular mechanism essential for maintaining
internal stability, plays a crucial function in female reproductive ability. In this review, we …
internal stability, plays a crucial function in female reproductive ability. In this review, we …
Dual-Activated H2O2-Responsive AIE Probes for Oocyte Quality Assessment
Nonobstructive azoospermia (NOA) is an important cause of infertility, and intracytoplasmic
sperm injection (ICSI) is the mainstay of treatment for these patients. In cases where a …
sperm injection (ICSI) is the mainstay of treatment for these patients. In cases where a …