Background Inhibitors of the sodium-glucose cotransporter 2 (SGLT2) slow the progression
of diabetic kidney disease, possibly by reducing the proximal tubule transport workload with …

Objectives Renal blood flow (RBF) is controlled by a number of physiological factors that can
contribute to the variability of its measurement. The purpose of this review is to assess the …

Background Renal hypoperfusion has been suggested to contribute to the development of
acute kidney injury (AKI) in critical COVID-19. However, limited data exist to support this. We …

Exercise is restricted for individuals with reduced renal function because exercising reduces
blood flow to the kidneys. Safe and effective exercise programs for individuals with reduced …

Background Changes in renal perfusion may play a pathophysiological role in hypertension
and kidney disease, however to date, no method for renal blood flow (RBF) determination in …

The Earth's rotation generates environmental oscillations (eg, in light and temperature) that
have imposed unique evolutionary pressures over millions of years. Consequently, the …

Study design and data analysis are two important aspects relevant to
chronopharmacometrics. Blunders can be avoided by recognizing that most physiological …

Background MRI can provide information on kidney structure, perfusion, and oxygenation.
Furthermore, it allows for the assessment of kidney sodium concentrations and handling …

Purpose Assessing renal perfusion in‐vivo is challenging and quantitative information
regarding renal hemodynamics is hardly incorporated in medical decision‐making while …

A spot urine creatinine‐to‐osmolality ratio (sUCr/Osm) is proposed as a surrogate of the
urinary excretion rate of creatinine (Cr) and convenient for forecasting serum Cr (SCr) …