Leishmaniasis (visceral and cutaneous), Chagas disease and human African
trypanosomiasis cause substantial death and morbidity, particularly in low-and middle …

Leishmania is a genus of parasitic protozoa that causes a disease called leishmaniasis.
Leishmaniasis is transmitted to humans through the bites of infected female sandflies. There …

Cutaneous leishmaniasis (CL) is a very common parasitic infection in subtropical areas
worldwide. Throughout decades, there have been challenges in vaccine design and …

Leishmania infections are global, occurring in 98 countries and all World Health
Organization (WHO) regions with 600 million to 1 billion people at risk of infection. Visceral …

The leishmaniases are globally important parasitic diseases for which no human vaccines
are currently available. To facilitate vaccine development, we conducted an open-label …

Understanding the immune response to Leishmania infection and identifying biomarkers
that correlate with protection are crucial for developing effective vaccines. One intriguing …

Leishmania parasites cause a variety of discrete clinical diseases that present in regions
where their specific sand fly vectors sustain transmission. Clinical and laboratory research …

This study aimed to investigate the in vitro and in silico antileishmanial activity of azacitidine
(AZA) on Leishmania major promastigotes and amastigotes. The in silico method was used …

Introduction: Leishmaniasis is a disease with high mortality rates and approximately 1.5
million new cases each year. Despite the new approaches and advances to fight the …

Visceral Leishmaniasis (VL) has a high death rate, with 500,000 new cases and 50,000
deaths occurring annually. Despite the development of novel strategies and technologies …