Pathophysiology of sickle cell disease

P Sundd, MT Gladwin, EM Novelli - Annual review of pathology …, 2019 - annualreviews.org
Since the discovery of sickle cell disease (SCD) in 1910, enormous strides have been made
in the elucidation of the pathogenesis of its protean complications, which has inspired recent …

Risk factors and prevention of hepatocellular carcinoma in the era of precision medicine

N Fujiwara, SL Friedman, N Goossens, Y Hoshida - Journal of hepatology, 2018 - Elsevier
Patients who develop chronic fibrotic liver disease, caused by viral or metabolic aetiologies,
are at a high risk of developing hepatocellular carcinoma (HCC). Even after complete HCC …

Liposome-Embedded Cu2–xAgxS Nanoparticle-Mediated Photothermal Immunoassay for Daily Monitoring of cTnI Protein Using a Portable Thermal Imager

Z Yu, H Gong, J Xu, Y Li, F Xue, Y Zeng, X Liu… - Analytical …, 2022 - ACS Publications
Functional photothermal nanomaterials have gained widespread attention in the field of
precise cancer therapy and early disease diagnosis due to their unique photothermal …

RNAi-based treatment of chronically infected patients and chimpanzees reveals that integrated hepatitis B virus DNA is a source of HBsAg

CI Wooddell, MF Yuen, HLY Chan, RG Gish… - Science translational …, 2017 - science.org
Chronic hepatitis B virus (HBV) infection is a major health concern worldwide, frequently
leading to liver cirrhosis, liver failure, and hepatocellular carcinoma. Evidence suggests that …

[HTML][HTML] 2018 Korean Liver Cancer Association–National Cancer Center Korea practice guidelines for the management of hepatocellular carcinoma

Korean Liver Cancer Association - Korean Journal of Radiology, 2019 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the fifth most common cancer globally and the fourth
most common cancer in men in Korea, where the prevalence of chronic hepatitis B infection …

[HTML][HTML] Causes of death among cancer patients

NG Zaorsky, TM Churilla, BL Egleston, SG Fisher… - Annals of oncology, 2017 - Elsevier
Background The purpose of our study was to characterize the causes of death among
cancer patients as a function of objectives:(i) calendar year,(ii) patient age, and (iii) time after …

[HTML][HTML] Lipid accumulation and chronic kidney disease

Z Gai, T Wang, M Visentin, GA Kullak-Ublick, X Fu… - Nutrients, 2019 - mdpi.com
Obesity and hyperlipidemia are the most prevalent independent risk factors of chronic
kidney disease (CKD), suggesting that lipid accumulation in the renal parenchyma is …

Role and mechanisms of cytokines in the secondary brain injury after intracerebral hemorrhage

H Zhu, Z Wang, J Yu, X Yang, F He, Z Liu, F Che… - Progress in …, 2019 - Elsevier
Intracerebral hemorrhage (ICH) is a common and severe cerebrovascular disease that has
high mortality. Few survivors achieve self-care. Currently, patients receive only symptomatic …

[HTML][HTML] Deep-learning-based cardiovascular risk stratification using coronary artery calcium scores predicted from retinal photographs

TH Rim, CJ Lee, YC Tham, N Cheung, M Yu… - The Lancet Digital …, 2021 - thelancet.com
Background Coronary artery calcium (CAC) score is a clinically validated marker of
cardiovascular disease risk. We developed and validated a novel cardiovascular risk …

[HTML][HTML] NLRP3 inflammasome assembly in neutrophils is supported by PAD4 and promotes NETosis under sterile conditions

P Münzer, R Negro, S Fukui, L Di Meglio… - Frontiers in …, 2021 - frontiersin.org
Neutrophil extracellular trap formation (NETosis) and the NLR family pyrin domain
containing 3 (NLRP3) inflammasome assembly are associated with a similar spectrum of …