Ischemic stroke is caused primarily by an interruption in cerebral blood flow, which induces
severe neural injuries, and is one of the leading causes of death and disability worldwide …

Brain fluids are rigidly regulated to provide stable environments for neuronal function, eg,
low K+, Ca 2+, and protein to optimise signalling and minimise neurotoxicity. At the same …

According to the traditional understanding of cerebrospinal fluid (CSF) physiology, the
majority of CSF is produced by the choroid plexus, circulates through the ventricles, the …

Traumatic brain injury (TBI) is a major cause of death in the young age group and leads to
persisting neurological impairment in many of its victims. It may result in permanent …

There has been significant progress in our understanding of the pathology and
pathogenesis of central nervous system inflammatory demyelinating diseases …

Brain edema leading to an expansion of brain volume has a crucial impact on morbidity and
mortality following traumatic brain injury (TBI) as it increases intracranial pressure, impairs …

The delivery of many potentially therapeutic and diagnostic compounds to specific areas of
the brain is restricted by brain barriers, of which the most well known are the blood–brain …

Advances in neuroimaging have enabled greater understanding of the progression of
cerebral degenerative processes associated with ageing‐related dementias. Leukoaraiosis …

Focal cerebral ischaemia and post-ischaemic reperfusion cause cerebral capillary
dysfunction, resulting in oedema formation and haemorrhagic conversion. There are …

Our understanding of the movement of water through cell membranes has been greatly
advanced by the discovery of a family of water-specific, membrane-channel proteins—the …