miRNAs as potential game-changers in renal cell carcinoma: Future clinical and medicinal uses
Renal cell carcinoma (RCC) has the highest mortality rate of all genitourinary cancers, and
its prevalence has grown over time. While RCC can be surgically treated and recurrence is …
its prevalence has grown over time. While RCC can be surgically treated and recurrence is …
[HTML][HTML] Noncoding RNAs related to the hedgehog pathway in cancer: clinical implications and future perspectives
J Song, Y Ge, X Sun, Q Guan, S Gong, M Wei, J Niu… - Molecular cancer, 2022 - Springer
Cancer is a type of malignant affliction threatening human health worldwide; however, the
molecular mechanism of cancer pathogenesis remains to be elusive. The oncogenic …
molecular mechanism of cancer pathogenesis remains to be elusive. The oncogenic …
[HTML][HTML] Circular RNA circPOLR2A promotes clear cell renal cell carcinoma progression by facilitating the UBE3C-induced ubiquitination of PEBP1 and, thereby …
Z Xu, S Chen, R Liu, H Chen, B Xu, W Xu, M Chen - Molecular Cancer, 2022 - Springer
Background Increasing evidence has demonstrated that circular RNAs (circRNAs) are
implicated in cancer progression. However, the aberrant expression and biological functions …
implicated in cancer progression. However, the aberrant expression and biological functions …
[HTML][HTML] Domain generalization enables general cancer cell annotation in single-cell and spatial transcriptomics
Z Zhong, J Hou, Z Yao, L Dong, F Liu, J Yue… - Nature …, 2024 - nature.com
Single-cell and spatial transcriptome sequencing, two recently optimized transcriptome
sequencing methods, are increasingly used to study cancer and related diseases. Cell …
sequencing methods, are increasingly used to study cancer and related diseases. Cell …
[HTML][HTML] Transfection with Plasmid-Encoding lncRNA-SLERCC nanoparticle-mediated delivery suppressed tumor progression in renal cell carcinoma
Background The accumulating evidence confirms that long non-coding RNAs (lncRNAs)
play a critical regulatory role in the progression of renal cell carcinoma (RCC). But, the …
play a critical regulatory role in the progression of renal cell carcinoma (RCC). But, the …
circCAPRIN1 interacts with STAT2 to promote tumor progression and lipid synthesis via upregulating ACC1 expression in colorectal cancer
Y Yang, D Luo, Y Shao, Z Shan, Q Liu… - Cancer …, 2023 - Wiley Online Library
Abstract Background Circular RNAs (circRNAs) generated by back‐splicing of precursor
mRNAs (pre‐mRNAs) are often aberrantly expressed in cancer cells. Accumulating …
mRNAs (pre‐mRNAs) are often aberrantly expressed in cancer cells. Accumulating …
[HTML][HTML] ELF5 drives angiogenesis suppression though stabilizing WDTC1 in renal cell carcinoma
T Li, L Xu, Z Wei, S Zhang, X Liu, Y Yang, Y Gu… - Molecular cancer, 2023 - Springer
Background Renal cell carcinoma (RCC) is a common malignant tumor of the urinary
system. Angiogenesis is a main contributing factor for tumorigenesis. E74-like transcription …
system. Angiogenesis is a main contributing factor for tumorigenesis. E74-like transcription …
[HTML][HTML] CircRNAs in lung cancer-role and clinical application
J Li, Q Zhang, D Jiang, J Shao, W Li, C Wang - Cancer Letters, 2022 - Elsevier
Lung cancer holds the highest mortality rate among malignancies worldwide. Nevertheless,
the potential molecular mechanisms of its tumorigenesis and evolution remain obscure …
the potential molecular mechanisms of its tumorigenesis and evolution remain obscure …
The roles and mechanisms of circular RNAs related to mTOR in cancers
C Cao, Y Wang, X Wu, Z Li, J Guo… - Journal of Clinical …, 2022 - Wiley Online Library
Abstract Background Circular RNAs (circRNAs) are stable molecules with covalently closed
structures that have an irreplaceable role in the occurrence, progression, and even …
structures that have an irreplaceable role in the occurrence, progression, and even …
Circular RNA KIF4A promotes liver metastasis of breast cancer by reprogramming glucose metabolism
J Huang, X Deng, X Chen, Z Chang, Q Lu… - Journal of …, 2022 - Wiley Online Library
Background. Circular RNAs (circRNAs) regulate complex functional processes and play
crucial roles in cancer development and progression. It was reported that circKIF4 regulates …
crucial roles in cancer development and progression. It was reported that circKIF4 regulates …