The present review provides a summary of recent evidence of sortilin expression, function,
and regulation and its implications in lipid metabolism and development of lipid disorder …

A cluster of three genes CELSR2, PSRC1, and SORT1 has been associated with
cardiovascular diseases. Thus, the aim of this study was (i) to perform a systematic review …

Lipid metabolism may be involved in the pathogenic mechanism of age-related macular
degeneration (AMD). However, conflicting results have been reported in the associations of …

Background: Antithrombin, PC (protein C), and PS (protein S) are circulating natural
anticoagulant proteins that regulate hemostasis and of which partial deficiencies are causes …

Background Cardiovascular disease is one of the most common causes of morbidity and
mortality worldwide. Several cardiovascular diseases require therapy with warfarin, an …

Background Dyslipidemia is recognized as one of the risk factors of cardiovascular diseases
(CVDs), type 2 diabetes mellitus (T2DM), and non‐alcoholic fatty liver disease (NAFLD) …

We evaluated the association between beta-adrenergic receptor genes (ADRB1 and
ADRB2) polymorphism, cardiovascular risk, and acute coronary syndrome (ACS) in …

Statistical methods to integrate multiple layers of data, from exposures to intermediate traits
to outcome variables, are needed to guide interpretation of complex data sets for which …

Background and Objectives: Coronary artery disease (CAD) is a major health problem in
México. The identification of modifiable risk factors and genetic biomarkers is crucial for an …

Familial hypercholesterolemia is one of the major causes of cardiovascular diseases, mainly
characterized by increased LDL and total cholesterol levels in the blood. It has been …