Oral tumor heterogeneity, its implications for patient monitoring and designing anti-cancer strategies

R Mishra - Pathology-Research and Practice, 2023 - Elsevier
Oral cancer tumors occur in the mouth and are mainly derived from oral mucosa linings. It is
one of the most common and fatal malignant diseases worldwide. The intratumor …

Clear Cell Squamous Cell Carcinoma of the Maxillary Gingiva Associated with PIK3CA and HRAS Mutations: Report of a Case and Literature Review

K Hirose, T Shibahara, A Teramoto, Y Usami… - Head and Neck …, 2023 - Springer
Background Squamous cell carcinoma (SCC) is the most common oral malignancy, and
somatic mutations in some driver genes have been implicated in SCC development. Clear …

High PD-L1 expression on tumor cells indicates worse overall survival in advanced oral squamous cell carcinomas of the tongue and the floor of the mouth but not in …

ŁJ Adamski, A Starzyńska, P Adamska, M Kunc… - Biomedicines, 2021 - mdpi.com
The markers of the tumor microenvironment (TME) are promising prognostic and predictive
factors in oral squamous cell carcinoma (OSCC). The current study aims to analyze the …

Any role of PIK3CA and PTEN biomarkers in the prognosis in oral squamous cell carcinoma?

A Starzyńska, P Adamska, A Sejda… - Life, 2020 - mdpi.com
Oral squamous cell carcinoma (OSCC) accounts for 95% of the lesions in the oral cavity.
Despite development in OSCC management, the outcome is still unsatisfactory …

Antiapoptotic PON2 expression and its clinical implications in locally advanced oral squamous cell carcinoma

MV Kamal, RR Damerla, P Parida… - Cancer …, 2024 - Wiley Online Library
Locally advanced oral squamous cell carcinoma poses a significant challenge in oncology
due to its rising incidence and mortality rates. Despite therapeutic progress, understanding …

PAICS/DYRK3 Multienzyme Interactions as Coregulators of Purinosome Formation and Metabolism on Radioresistance in Oral Squamous Cell Carcinoma

CS Huang, MS Hsieh, VK Yadav, YC Wu… - International journal of …, 2023 - mdpi.com
Oral squamous cell carcinoma (OSCC) is a prevalent type of oral cancer. While therapeutic
innovations have made strides, radioresistance persists as a significant hindrance in OSCC …

[HTML][HTML] Knockdown of RNA-binding protein IMP3 suppresses oral squamous cell carcinoma proliferation by destabilizing E2F5 transcript

Z Wang, H Zhang, F Li, C Huang - Aging (Albany NY), 2024 - ncbi.nlm.nih.gov
The expression level of RNA-binding proteins (RBPs) is dysregulated in oral squamous cell
carcinoma (OSCC) and other types of cancer. Among the RBPs, IMP3 is involved in the …

Clinical and Histopathological Factors Associated with the Tumoral Expression of TGF‐β1, MED15, CD16, and CD57 in Oral Squamous Cell Carcinoma

M Elahi, V Rakhshan - Advances in Preventive Medicine, 2022 - Wiley Online Library
Introduction. Factors associated with the expression of oral squamous cell carcinoma
(OSCC) biomarkers “CD16, CD57, TGF‐β1, and MED15” are not assessed, except in few …

Squamous cell carcinoma initially occurring on the tongue dorsum: a case series report with molecular analysis

S Ono, K Hirose, S Sukegawa, K Obata, M Masui… - Diagnostic …, 2024 - Springer
Background Squamous cell carcinoma (SCC) of the dorsum of the tongue is extremely rare,
and it clinically resembles various benign lesions. Somatic mutations in TP53 and some …

Hippo‐YAP signaling activation and cross‐talk with PI3K in oral cancer: A retrospective cohort study

JP Rodrigo, T Rodríguez‐Santamarta, D Corte… - Oral …, 2024 - Wiley Online Library
Objectives This study aimed to investigate the clinical and prognostic relevance of the Hippo‐
YAP transactivators YAP1 and TAZ in oral squamous cell carcinoma, and their possible …