Significance: The stria vascularis, located in the inner ear, consists of three layers, one of
which is the blood–labyrinth barrier (BLB). It is formed by endothelial cells, sealed together …

Background and Objectives: Discussion is open about the relationship between diabetes
(DM) and hearing loss (HL). There is a lot of evidence in the literature suggesting a causal …

Alport syndrome (AS), a type IV collagen disorder, leads to glomerular disease and, in some
patients, hearing loss. AS is treated with inhibitors of the renin–angiotensin system; …

Mechanosensitive hair cells in the cochlea are responsible for hearing but are vulnerable to
damage by genetic mutations and environmental insults. The paucity of human cochlear …

TRPC channels are critical players in cochlear hair cells and sensory neurons, as
demonstrated in animal experiments. However, evidence for TRPC expression in the human …

Age-related hearing loss, or presbyacusis, is a common degenerative disorder affecting
communication and quality of life for millions of older adults. Multiple pathophysiologic …

Spiral ligament fibrocytes generate potassium gradients, which hair cells require to convert
mechanical sound waves into electrical palsy. Together with the stria vascularis, they …

Methods This study used an internal dataset of 203 digitized hematoxylin and eosin-stained
sections from a normal macaque ear and a separate external validation set of 10 sections …

The stria vascularis (SV) contributes to cochlear homeostasis and consists of three layers,
one of which contains the blood-labyrinthic barrier (BLB), with a large number of bovine …

Objective: The duration and quality of sleep have been associated with multiple health
conditions in adults. However, whether sleep duration and quality are associated with …