HIV UTR, LTR, and epigenetic immunity
J Zhang, C Crumpacker - Viruses, 2022 - mdpi.com
The duel between humans and viruses is unending. In this review, we examine the HIV RNA
in the form of un-translated terminal region (UTR), the viral DNA in the form of long terminal …
in the form of un-translated terminal region (UTR), the viral DNA in the form of long terminal …
Aid or antagonize: nuclear long noncoding RNAs regulate host responses and outcomes of viral infections
V Kulkarni, S Jayakumar, M Mohan, S Kulkarni - Cells, 2023 - mdpi.com
Long noncoding RNAs (lncRNAs) are transcripts measuring> 200 bp in length and devoid of
protein-coding potential. LncRNAs exceed the number of protein-coding mRNAs and …
protein-coding potential. LncRNAs exceed the number of protein-coding mRNAs and …
Role of virus-induced host cell epigenetic changes in cancer
V Pietropaolo, C Prezioso, U Moens - International Journal of Molecular …, 2021 - mdpi.com
The tumor viruses human T-lymphotropic virus 1 (HTLV-1), hepatitis C virus (HCV), Merkel
cell polyomavirus (MCPyV), high-risk human papillomaviruses (HR-HPVs), Epstein-Barr …
cell polyomavirus (MCPyV), high-risk human papillomaviruses (HR-HPVs), Epstein-Barr …
HTLV1 persistent infection and ATLL oncogenesis
X Zuo, R Zhou, S Yang, G Ma - Journal of Medical Virology, 2023 - Wiley Online Library
Human Tcell leukemia virus type 1 (HTLV1) was discovered in the 1980s, but it is
estimated to have been infecting humans for more than ten thousand years. 1 With over 90 …
estimated to have been infecting humans for more than ten thousand years. 1 With over 90 …
Current perspectives in human T-cell leukemia virus type 1 infection and its associated diseases
M Miura, T Naito, M Saito - Frontiers in Medicine, 2022 - frontiersin.org
Human T-cell leukemia virus type 1 (HTLV-1) is a replication-competent human retrovirus
associated with two distinct types of diseases: a malignancy of mature CD4+ T cells called …
associated with two distinct types of diseases: a malignancy of mature CD4+ T cells called …
Origin and functional role of antisense transcription in endogenous and exogenous retroviruses
F Romerio - Retrovirology, 2023 - Springer
Most proteins expressed by endogenous and exogenous retroviruses are encoded in the
sense (positive) strand of the genome and are under the control of regulatory elements …
sense (positive) strand of the genome and are under the control of regulatory elements …
Novel perspectives on antisense transcription in HIV-1, HTLV-1, and HTLV-2
The genome of retroviruses contains two promoter elements (called long terminal repeat or
LTR) at the 5′ and 3′ end of their genome. Although the expression of retroviral genes …
LTR) at the 5′ and 3′ end of their genome. Although the expression of retroviral genes …
HTLV-1 Hbz protein, but not hbz mRNA secondary structure, is critical for viral persistence and disease development
V Maksimova, T Wilkie, S Smith, C Phelps… - PLoS …, 2023 - journals.plos.org
Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic cause of adult T-cell
leukemia/lymphoma (ATL) and encodes a viral oncoprotein (Hbz) that is consistently …
leukemia/lymphoma (ATL) and encodes a viral oncoprotein (Hbz) that is consistently …
Activation of HIV-1 proviruses increases downstream chromatin accessibility
It is unclear how the activation of HIV-1 transcription affects chromatin structure. We
interrogated chromatin organization both genome-wide and nearby HIV-1 integration sites …
interrogated chromatin organization both genome-wide and nearby HIV-1 integration sites …
Recent insights into the functions and mechanisms of antisense RNA: emerging applications in cancer therapy and precision medicine
The antisense RNA molecule is a unique DNA transcript consisting of 19–23 nucleotides,
characterized by its complementary nature to mRNA. These antisense RNAs play a crucial …
characterized by its complementary nature to mRNA. These antisense RNAs play a crucial …