A Multifaceted Mass Spectrometric Method to Probe Feeding Related Neuropeptide Changes in Callinectes sapidus and Carcinus maenas

Y Zhang, K DeLaney, L Hui, J Wang… - Journal of the …, 2018 - ACS Publications
Food intake is regulated by various neuromodulators, including numerous neuropeptides.
However, it remains elusive at the molecular and cellular level as to how these important …

Metabolomics—a promising approach to pituitary adenomas

O Pînzariu, B Georgescu, CE Georgescu - Frontiers in endocrinology, 2019 - frontiersin.org
Background: Metabolomics—the novel science that evaluates the multitude of low-molecular-
weight metabolites in a biological system, provides new data on pathogenic mechanisms of …

Mapping of neuropeptides in the crustacean stomatogastric nervous system by imaging mass spectrometry

H Ye, L Hui, K Kellersberger, L Li - Journal of the American …, 2012 - ACS Publications
Considerable effort has been devoted to characterizing the crustacean stomatogastric
nervous system (STNS) with great emphasis on comprehensive analysis and mapping …

High throughput in situ DDA analysis of neuropeptides by coupling novel multiplex mass spectrometric imaging (MSI) with gas-phase fractionation

C OuYang, B Chen, L Li - Journal of The American Society for …, 2015 - ACS Publications
Matrix-assisted laser desorption/ionization (MALDI) mass spectrometric imaging (MSI) is a
powerful tool to map the spatial distribution of biomolecules on tissue sections. Recent …

Advances in high‐resolution maldi mass spectrometry for neurobiology

K DeLaney, A Phetsanthad, L Li - Mass spectrometry reviews, 2022 - Wiley Online Library
Research in the field of neurobiology and neurochemistry has seen a rapid expansion in the
last several years due to advances in technologies and instrumentation, facilitating the …

Mass spectrometric elucidation of the neuropeptidome of a crustacean neuroendocrine organ

L Hui, F Xiang, Y Zhang, L Li - Peptides, 2012 - Elsevier
The blue crab Callinectes sapidus has been used as an experimental model organism for
the study of regulation of cardiac activity and other physiological processes. Moreover, it is …

Detection of small molecule concentration gradients in ocular tissues and humours

BA Boughton, ORB Thomas… - Journal of mass …, 2020 - Wiley Online Library
The eye is an elegant organ consisting of a number of tissues and fluids with specialised
functions that together allow it to effectively transmit and transduce light input to the brain for …

Distribution and physiological effects of B‐type allatostatins (myoinhibitory peptides, MIPs) in the stomatogastric nervous system of the crab Cancer borealis

TM Szabo, R Chen, ML Goeritz… - Journal of …, 2011 - Wiley Online Library
The crustacean stomatogastric ganglion (STG) is modulated by a large number of amines
and neuropeptides that are found in descending pathways from anterior ganglia or reach the …

Combining Microdialysis, NanoLC-MS, and MALDI-TOF/TOF To Detect Neuropeptides Secreted in the Crab, Cancer borealis

HL Behrens, R Chen, L Li - Analytical chemistry, 2008 - ACS Publications
Microdialysis is a useful technique for sampling neuropeptides in vivo, and decapod
crustaceans are important model organisms for studying how these peptides regulate …

Comparative neuropeptidomic analysis of food intake via a multifaceted mass spectrometric approach

R Chen, L Hui, SS Cape, J Wang… - ACS chemical …, 2010 - ACS Publications
Feeding behavior is a fundamental aspect of energy homeostasis and is crucial for animal
survival. This process is regulated by a multitude of neurotransmitters including …