Hypopituitarism refers to deficiency of one or more hormones produced by the anterior
pituitary or released from the posterior pituitary. Hypopituitarism is associated with excess …

Prolactin (PRL) is secreted by the lactotroph cells in the anterior pituitary gland which is
under inhibitory control of dopamine. The mature human PRL has more than 300 …

Opinion statement Survival rates of childhood cancer have improved markedly, and today
more than 80% of those diagnosed with a pediatric malignancy will become 5-year …

The pituitary gland has a role in puberty, reproduction, stress-adaptive responses, sodium
and water balance, uterine contractions, lactation, thyroid function, growth, body composition …

Severe GH deficiency (GHD) in adults has been described as a clinical entity. However,
some of the features associated with GHD could be due to unphysiological and inadequate …

Background Whole-brain radiotherapy is a primary treatment for brain tumors and brain
metastasis, but it also induces long-term undesired effects. Since cognitive impairment can …

The GH/IGF1 system, like other endocrine systems, is dynamic and its activity changes with
age and sexual maturation, and is influenced by body composition and other factors. A …

Objectives Prolactin (PRL) is a multifunctional hormone that influences multiple
physiological processes. It has been shown to have a protective effect on the cardiovascular …

Acquired PRL deficiency occurs when the anterior pituitary is functionally destroyed, and it
usually accompanies other pituitary hormone deficiencies. We retrospectively investigated in …

Purpose We aimed to investigate the prevalence and the diagnostic criteria of
hypoprolactinemia in patients with panhypopituitarism and the effects of hypoprolactinemia …