Amyloid Neuropathy: From Pathophysiology to Treatment in Light‐Chain Amyloidosis and Hereditary Transthyretin Amyloidosis

P Chompoopong, ML Mauermann… - Annals of …, 2024 - Wiley Online Library
Amyloid neuropathy is caused by deposition of insoluble β‐pleated amyloid sheets in the
peripheral nervous system. It is most common in:(1) light‐chain amyloidosis, a clonal non …

Hematologic Disorders and the Nervous System

ML Mauermann, AM Southerland - … : Lifelong Learning in …, 2023 - journals.lww.com
Hematologic Disorders and the Nervous System : CONTINUUM: Lifelong Learning in Neurology
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[HTML][HTML] Pathway for development and validation of multi-domain endpoints for amyloid light chain (AL) amyloidosis

J Signorovitch, J Zhang, D Brown, P Dunnmon… - … Innovation & Regulatory …, 2024 - Springer
Immunoglobin light chain (AL) amyloidosis is a rare disease in which a plasma cell
dyscrasia leads to deposition of insoluble amyloid fibrils in multiple organs. To facilitate …

Amyloidosis of the urinary bladder: a systematic review and a proposed management algorithm

N Pyrgidis, I Mykoniatis, VF Pegios, I Sokolakis… - Urology, 2021 - Elsevier
Objective To propose an algorithm for the management of bladder amyloidosis based on a
systematic review of the literature, given that the bladder is the second most commonly …

The characteristics of patients with kidney light chain deposition disease concurrent with light chain amyloidosis

SM Said, AB Rocha, AM Valeri, P Paueksakon… - Kidney international, 2022 - Elsevier
The type of monoclonal light chain nephropathy is thought to be largely a function of the
structural and physiochemical properties of light chains; hence most affected patients have …

Renal amyloidosis: validation of a proposed histological scoring system in an independent cohort

JJ Hoelbeek, J Kers, EJ Steenbergen… - Clinical Kidney …, 2021 - academic.oup.com
Background In systemic amyloidosis, the kidney is frequently affected and renal involvement
has a major impact on survival. Renal involvement is clinically characterized by decreased …

of the World Health Classification of Tumors of the Hematopoietic and Lymphoid Tissues: B-cell Neoplasms

LJ Medeiros, A Chadburn, Y Natkunam, KN Naresh - Modern Pathology, 2024 - Elsevier
We review B-cell lymphomas in the 5th edition of the World Health Organization
classification of hematolymphoid tumors (WHO-HEM5). The revised classification is based …

[HTML][HTML] Advancing Renal Amyloidosis Care: The Role of Modern Diagnostic Techniques with the Potential of Enhancing Patient Outcomes

C Delrue, A Dendooven, A Vandendriessche… - International Journal of …, 2024 - mdpi.com
Renal amyloidosis is a set of complex disorders characterized by the deposition of amyloid
proteins in the kidneys, which causes gradual organ damage and potential kidney failure …

Cardiac amyloidosis: an update on diagnosis, current therapy, and future directions

R Khedraki - Current Opinion in Cardiology, 2022 - journals.lww.com
Cardiac amyloidosis: an update on diagnosis, current therapy... : Current Opinion in Cardiology
Cardiac amyloidosis: an update on diagnosis, current therapy, and future directions : Current …

Non-invasive diagnosis of transthyretin cardiac amyloidosis utilizing typical late gadolinium enhancement pattern on cardiac magnetic resonance and light chains

JA Slivnick, N Alvi, CC Singulane… - European Heart …, 2023 - academic.oup.com
Aims While cardiac magnetic resonance (CMR) is often obtained early in the evaluation of
suspected cardiac amyloidosis (CA), it currently cannot be utilized to differentiate …