Molecular mechanisms of the antitumor effects of mesalazine and its preventive potential in colorectal cancer
J Słoka, M Madej, B Strzalka-Mrozik - Molecules, 2023 - mdpi.com
Chemoprevention is one of the ways to fight colorectal cancer, which is a huge challenge in
oncology. Numerous pieces of evidence indicate that chronic inflammation in the course of …
oncology. Numerous pieces of evidence indicate that chronic inflammation in the course of …
Intervention and potential mechanism of non-starch polysaccharides from natural resources on ulcerative colitis: A review
YJ Wang, QM Li, XQ Zha, JP Luo - International Journal of Biological …, 2022 - Elsevier
Ulcerative colitis (UC) is a chronic inflammatory bowel disease of unknown etiology that
affects the colon and rectum. It has evolved into a global burden due to the high incidence in …
affects the colon and rectum. It has evolved into a global burden due to the high incidence in …
ABX464 (obefazimod) for moderate-to-severe, active ulcerative colitis: a phase 2b, double-blind, randomised, placebo-controlled induction trial and 48 week, open …
Background ABX464 (obefazimod) is a small molecule that selectively upregulates miR-124
in immune cells. We aimed to assess ABX464 as a treatment for patients with moderate-to …
in immune cells. We aimed to assess ABX464 as a treatment for patients with moderate-to …
Protocatechuic acid alleviates dextran-sulfate-sodium-induced ulcerative colitis in mice via the regulation of intestinal flora and ferroptosis
X Yang, X Sun, F Zhou, S Xiao, L Zhong, S Hu, Z Zhou… - Molecules, 2023 - mdpi.com
Protocatechuic acid (PCA) is a natural component with multiple biological activities.
However, the underlying mechanisms of the effects of PCA on anti-ulcerative colitis (UC) are …
However, the underlying mechanisms of the effects of PCA on anti-ulcerative colitis (UC) are …
[HTML][HTML] The latest progress of natural food polysaccharides preventing ulcerative colitis by regulating intestinal microbiota
X Pan, M Yin, M Guo, X Niu, L Han - Journal of Functional Foods, 2022 - Elsevier
The incidence of ulcerative colitis (UC) is increasing annually and tends to inflict younger
individuals, and seriously affects daily work, study, and physical and mental health …
individuals, and seriously affects daily work, study, and physical and mental health …
The role of dietary fibers in the management of IBD symptoms
C Di Rosa, A Altomare, E Imperia, C Spiezia… - Nutrients, 2022 - mdpi.com
Inflammatory bowel diseases (IBDs) are chronic, progressive, immune-mediated diseases of
the intestinal tract. The main subtypes of IBDs are Chron's disease (CD) and ulcerative …
the intestinal tract. The main subtypes of IBDs are Chron's disease (CD) and ulcerative …
Efficacy and safety of gut microbiota-based therapies in autoimmune and rheumatic diseases: a systematic review and meta-analysis of 80 randomized controlled …
Background Previous randomized controlled trials (RCTs) suggested that gut microbiota-
based therapies may be effective in treating autoimmune diseases, but a systematic …
based therapies may be effective in treating autoimmune diseases, but a systematic …
Macrophage‐Biomimetic Nanoplatform‐Based Therapy for Inflammation‐Associated Diseases
Y Qu, B Chu, J Li, H Deng, T Niu, Z Qian - Small Methods, 2023 - Wiley Online Library
Inflammation‐associated diseases are very common clinically with a high incidence;
however, there is still a lack of effective treatments. Cell‐biomimetic nanoplatforms have led …
however, there is still a lack of effective treatments. Cell‐biomimetic nanoplatforms have led …
Effects of medicinal plants and phytochemicals in Nrf2 pathways during inflammatory bowel diseases and related colorectal cancer: A comprehensive review
LF Laurindo, MC de Maio, G Minniti, N de Góes Corrêa… - Metabolites, 2023 - mdpi.com
Inflammatory bowel diseases (IBDs) are related to nuclear factor erythroid 2-related factor 2
(Nrf2) dysregulation. In vitro and in vivo studies using phytocompounds as modulators of the …
(Nrf2) dysregulation. In vitro and in vivo studies using phytocompounds as modulators of the …
[HTML][HTML] Dendrobium huoshanense in the treatment of ulcerative colitis: Network pharmacology and experimental validation
L Yao, J Fang, J Zhao, J Yu, X Zhang, W Chen… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Dendrobium huoshanense CZ Tang et SJ Cheng (DH) is a
traditional medicinal herb with a long history of medicinal use. DH has been recorded as …
traditional medicinal herb with a long history of medicinal use. DH has been recorded as …