PCSK9 promotes tumor cell proliferation and migration by facilitating CCL25 secretion in esophageal squamous cell carcinoma
H Wang, Q Guo, M Wang, C Liu… - Oncology …, 2023 - spandidos-publications.com
Proprotein convertase subtilisin/kexin type 9 (PCSK9) serves an important role in
maintaining plasma cholesterol levels, and fatty acid metabolism is involved in the …
maintaining plasma cholesterol levels, and fatty acid metabolism is involved in the …
Antitumor progestins activity: Cytostatic effect and immune response
T Pavlik, E Konchekov, N Shimanovskii - Steroids, 2024 - Elsevier
Progestins are used to treat some hormone-sensitive tumors. This review discusses the
mechanisms of progestins' effects on tumor cells, the differences in the effects of …
mechanisms of progestins' effects on tumor cells, the differences in the effects of …
Fine particulate matter promotes airway inflammation and mucin production by activating endoplasmic reticulum stress and the IRE1α/NOD1/NF‑κB pathway
L Hu, C Xu, X Tang, S Yu… - International …, 2023 - spandidos-publications.com
Abstract Fine particulate matter (PM2. 5) is a type of small particle that is< 2.5 µm in diameter
that may cause airway inflammation. Thus, the present study aimed to explore the effects of …
that may cause airway inflammation. Thus, the present study aimed to explore the effects of …
Doxazosin inhibits vasculogenic mimicry in human non‑small cell lung cancer through inhibition of the VEGF‑A/VE‑cadherin/mTOR/MMP pathway
JL Hsu, WJ Leu, LC Hsu, CH Hsieh… - Oncology …, 2024 - spandidos-publications.com
Lung cancer is the leading cause of cancer‑related death worldwide, and~ 85% of lung
cancers are non‑small cell lung cancer (NSCLC), which has a low 5‑year overall survival …
cancers are non‑small cell lung cancer (NSCLC), which has a low 5‑year overall survival …
[HTML][HTML] m6A demethylase ALKBH5 maintains stemness of intrahepatic cholangiocarcinoma by sustaining BUB1B expression and cell proliferation
Y Gao, M Yu, Z Liu, Y Liu, Z Kong, C Zhu, X Qin… - Translational …, 2024 - Elsevier
ALKBH5 plays critical roles in various cellular processes via post-transcriptional regulation
of oncogenes or tumor suppressors in an N6-methyladenosine (m6A)-dependent manner …
of oncogenes or tumor suppressors in an N6-methyladenosine (m6A)-dependent manner …
[HTML][HTML] Succinylation of 14–3–3 theta by CPT1A promotes survival and paclitaxel resistance in nasal type extranodal natural killer/T-cell lymphoma
X Cui, C Cao, X Li, B Lin, A Yan, Y Yang - Translational Oncology, 2024 - Elsevier
Background The aggressive and refractory extranodal natural killer/T-cell lymphoma, nasal
type (ENKTL-NT) is a subtype of non-Hodgkin's lymphoma. Succinylation promotes …
type (ENKTL-NT) is a subtype of non-Hodgkin's lymphoma. Succinylation promotes …
Single domain antibodies specific for HER2 dimerization domain effectively disrupts HER2 dimerization
Dimer-dependent phosphorylation of HER2 receptor is a key event for the signal
transduction of HER family of receptors which correlates with tumor invasion and metastasis …
transduction of HER family of receptors which correlates with tumor invasion and metastasis …
Role of C/EBP Homologous Protein (CHOP) and Nupr1 Interaction in Endoplasmic Reticulum Stress-Induced Apoptosis of Lens Epithelial Cells
J Li, J Liu, Y Tang, H Zhang, Y Zhang, X Zha… - Molecular …, 2024 - Springer
Our study mainly analyzed the mechanism of C/EBP homologous protein (CHOP) and its
interacting protein Nupr1 on endoplasmic reticulum stress (ERS) induced lens epithelial …
interacting protein Nupr1 on endoplasmic reticulum stress (ERS) induced lens epithelial …
Rapamycin inhibits B16 melanoma cell viability in vitro and in vivo by inducing autophagy and inhibiting the mTOR/p70‑S6k pathway
P Wang, H Zhang, K Guo, C Liu, S Chen… - Oncology …, 2024 - spandidos-publications.com
Rapamycin is an immunosuppressant that has been shown to prevent tumor growth
following organ transplantation. However, its exact mode of antitumor action remains …
following organ transplantation. However, its exact mode of antitumor action remains …
Obtusifolin inhibits podocyte apoptosis by inactivating NF-κB signaling in acute kidney injury
H Xiang, Y Wu, Y Zhang, Y Hong, Y Xu - Cytotechnology, 2024 - Springer
Acute kidney injury (AKI) is a common clinical condition and is associated with unacceptable
morbidity and mortality. Obtusifolin is an anthraquinone extracted from the seeds of Cassia …
morbidity and mortality. Obtusifolin is an anthraquinone extracted from the seeds of Cassia …