Prognostic implication of BRAF and TERT promoter mutation combination in papillary thyroid carcinoma—a meta‐analysis

HG Vuong, AMA Altibi, UNP Duong… - Clinical …, 2017 - Wiley Online Library
Introduction The use of molecular markers, especially BRAF and TERT promoter mutations,
for risk stratification in papillary thyroid carcinoma (PTC) is subject to continuing debate. In …

[HTML][HTML] Radioactive iodine-refractory differentiated thyroid cancer and redifferentiation therapy

J Liu, Y Liu, Y Lin, J Liang - Endocrinology and Metabolism, 2019 - ncbi.nlm.nih.gov
The retained functionality of the sodium iodide symporter (NIS) expressed in differentiated
thyroid cancer (DTC) cells allows the further utilization of post-surgical radioactive iodine …

[PDF][PDF] Genetic landscape of somatic mutations in a large cohort of sporadic medullary thyroid carcinomas studied by next-generation targeted sequencing

R Ciampi, C Romei, T Ramone, A Prete, A Tacito… - IScience, 2019 - cell.com
Summary Sporadic Medullary Thyroid Carcinoma (sMTC) is a rare but aggressive thyroid
tumor. RET and RAS genes are present in about 50%–80% of cases, but most of the …

Molecular pathology of anaplastic thyroid carcinomas: a retrospective study of 144 cases

B Bonhomme, Y Godbert, G Perot, A Al Ghuzlan… - Thyroid, 2017 - liebertpub.com
Background: Anaplastic thyroid carcinoma (ATC) is a rare tumor, with poorly defined
oncogenic molecular mechanisms and limited therapeutic options contributing to its poor …

[Retracted] Risk Factors for TERT Promoter Mutations with Papillary Thyroid Carcinoma Patients: A Meta‐Analysis and Systematic Review

J Mao, X Huang, MK Okla… - … Methods in Medicine, 2022 - Wiley Online Library
Whether TERT promoter mutation is related to more aggressive clinicopathologic features
and worse outcomes in papillary thyroid carcinoma patients (PTCs) is still variable and …

[HTML][HTML] Frequency of TERT promoter mutations in real-world analysis of 2,092 thyroid carcinoma patients

H Yang, H Park, HJ Ryu, J Heo, JS Kim… - Endocrinology and …, 2022 - ncbi.nlm.nih.gov
Background Telomerase reverse transcriptase (TERT) promoter mutations are associated
with increased recurrence and mortality in patients with thyroid carcinoma. Previous studies …

[HTML][HTML] A meta-analysis of prognostic roles of molecular markers in papillary thyroid carcinoma

HG Vuong, UNP Duong, AMA Altibi… - Endocrine …, 2017 - ec.bioscientifica.com
The prognostic role of molecular markers in papillary thyroid carcinoma (PTC) is a matter of
ongoing debate. The aim of our study is to investigate the impact of RAS, BRAF, TERT …

Clinical significance and diagnostic value of QPCT, SCEL and TNFRSF12A in papillary thyroid cancer

T Liang, X Wu, L Wang, Z Ni, Y Fan, P Wu… - … -Research and Practice, 2023 - Elsevier
Purpose To identify specific novel genes that could be used as diagnostic and prognostic
factors in papillary thyroid carcinoma (PTC). Methods Screening of differential genes by …

TERT mRNA Expression as a Novel Prognostic Marker in Papillary Thyroid Carcinomas

A Tanaka, M Matsuse, V Saenko, T Nakao… - Thyroid, 2019 - liebertpub.com
Background: Telomerase reverse transcriptase (TERT) promoter mutations have been found
in a subset of papillary thyroid carcinomas (PTCs) and are associated with tumor …

Genetic-guided risk assessment and management of thyroid cancer

M Xing - Endocrinology and Metabolism Clinics, 2019 - endo.theclinics.com
Thyroid cancer is a common endocrine malignancy, which histologically includes follicular
epithelial cell–derived thyroid cancer and parafollicular C-cell–derived medullary thyroid …