[HTML][HTML] Functional imaging for assessing regional lung ventilation in preclinical and clinical research

D Karmali, M Sowho, S Bose, J Pearce… - Frontiers in …, 2023 - frontiersin.org
Dynamic heterogeneity in lung ventilation is an important measure of pulmonary function
and may be characteristic of early pulmonary disease. While standard indices like …

[HTML][HTML] Quantifying ventilation by X-ray velocimetry in healthy adults

T Siddharthan, K Grealis, JP Kirkness, T Ötvös… - Respiratory …, 2023 - Springer
Rationale X-ray velocimetry (XV) has been utilized in preclinical models to assess lung
motion and regional ventilation, though no studies have compared XV-derived physiologic …

Findings on high resolution computed tomography in symptomatic veterans with deployment-related lung disease

CS Rose, LM Zell-Baran, C Cool… - Journal of Thoracic …, 2023 - journals.lww.com
Purpose: Military deployment to dusty, austere environments in Southwest Asia and
Afghanistan is associated with symptomatic airways diseases including asthma and …

Regional variations in allergen‐induced airway inflammation correspond to changes in soluble guanylyl cyclase heme and expression of heme oxygenase‐1

MP Sumi, R Westcott, E Stuehr, C Ghosh… - The FASEB …, 2024 - Wiley Online Library
Asthma is characterized by airway remodeling and hyperreactivity. Our earlier studies
determined that the nitric oxide (NO)–soluble guanylyl cyclase (sGC)–cGMP pathway plays …

Regions of Inflammation in mouse asthma correspond to regions of heme-free soluble guanylyl cyclase and can be tracked by marked expression of heme-oxygenase …

MP Sumi, R Westcott, E Stuehr, C Ghosh, DJ Stuehr… - bioRxiv, 2023 - biorxiv.org
Asthma is characterized by airway remodeling and hyperreactivity. Our earlier studies
determined that the Nitric Oxide (NO)-soluble Guanylyl Cyclase (sGC)-cGMP pathway plays …