[HTML][HTML] Monoclonal antibodies and invasive aspergillosis: diagnostic and therapeutic perspectives

X Lian, A Scott-Thomas, JG Lewis, M Bhatia… - International Journal of …, 2022 - mdpi.com
Invasive aspergillosis (IA) is a life-threatening fungal disease that causes high morbidity and
mortality in immunosuppressed patients. Early and accurate diagnosis and treatment of IA …

Longitudinal in vivo microcomputed tomography of mouse lungs: No evidence for radiotoxicity

G Vande Velde, E De Langhe… - … of Physiology-Lung …, 2015 - journals.physiology.org
Before microcomputed tomography (micro-CT) can be exploited to its full potential for
longitudinal monitoring of transgenic and experimental mouse models of lung diseases …

[HTML][HTML] From mouse to man and back: closing the correlation gap between imaging and histopathology for lung diseases

B Tielemans, K Dekoster, SE Verleden, S Sawall… - Diagnostics, 2020 - mdpi.com
Lung diseases such as fibrosis, asthma, cystic fibrosis, infection and cancer are life-
threatening conditions that slowly deteriorate quality of life and for which our diagnostic …

[HTML][HTML] Integrating small animal irradiators with functional imaging for advanced preclinical radiotherapy research

M Ghita, KH Brown, OJ Kelada, EE Graves… - Cancers, 2019 - mdpi.com
Translational research aims to provide direct support for advancing novel treatment
approaches in oncology towards improving patient outcomes. Preclinical studies have a …

In vivo pentamodal tomographic imaging for small animals

M Liu, H Guo, H Liu, Z Zhang, C Chi, H Hui… - Biomedical optics …, 2017 - opg.optica.org
Multimodality molecular imaging emerges as a powerful strategy for correlating multimodal
information. We developed a pentamodal imaging system which can perform positron …

A Multimodal Imaging Approach Enables In Vivo Assessment of Antifungal Treatment in a Mouse Model of Invasive Pulmonary Aspergillosis

J Poelmans, U Himmelreich, L Vanherp… - Antimicrobial Agents …, 2018 - Am Soc Microbiol
Aspergillus fumigatus causes life-threatening lung infections in immunocompromised
patients. Mouse models are extensively used in research to assess the in vivo efficacies of …

Noninvasive imaging of experimental lung fibrosis

Y Zhou, H Chen, N Ambalavanan, G Liu… - American Journal of …, 2015 - atsjournals.org
Small animal models of lung fibrosis are essential for unraveling the molecular mechanisms
underlying human fibrotic lung diseases; additionally, they are useful for preclinical testing of …

Ethanol fixation method for heart and lung imaging in micro-CT

M Patzelt, J Mrzilkova, J Dudak, F Krejci… - Japanese Journal of …, 2019 - Springer
Purpose The soft tissue imaging in micro-CT remains challenging due to its low intrinsic
contrast. The aim of this study was to create a simple staining method omitting the usage of …

[HTML][HTML] Establishing a 4D-CT lung function related volumetric dose model to reduce radiation pneumonia

C Liu, H Liu, Y Li, Z Xiao, Y Wang, H Guo, J Luo - Scientific Reports, 2024 - nature.com
In order to study how to use pulmonary functional imaging obtained through 4D-CT fusion
for radiotherapy planning, and transform traditional dose volume parameters into functional …

Tracking of inhaled near-infrared fluorescent nanoparticles in lungs of SKH-1 mice with allergic airway inflammation

MA Markus, J Napp, T Behnke, M Mitkovski… - ACS …, 2015 - ACS Publications
Molecular imaging of inflammatory lung diseases, such as asthma, has been limited to date.
The recruitment of innate immune cells to the airways is central to the inflammation process …