Numerous publications have documented that the immortal cells grown in three-dimensional
(3D) cultures possess physiological behavior, which is more reminiscent of their parental …

Potential hepatotoxicity related to amiodarone therapy is often a concern when deciding
whether to initiate or continue treatment with this medication. While mostly associated with …

Featuring more than 4100 references, Drug-Induced Liver Disease is an invaluable
reference for gastroenterologists, hepatologists, family physicians, internists, pathologists …

Many drugs, including most antiarrhythmics (some of which are now of limited clinical use)
are eliminated by the hepatic route. If liver function is impaired, it can be anticipated that …

Drug‐induced liver injury (DILI) encompasses a spectrum of liver diseases from acute and
chronic hepatitis, cholestatic syndromes, and vascular lesions through to benign and …

Background Acetaminophen administration for more than 4 days causes aminotransferase
elevation in some subjects. The objective of this randomized, placebo-controlled trial is to …

Introduction. Amiodarone has been used for more than 5 decades for the treatment of
various tachyarrhythmias and previously for the treatment of refractory angina. There are …

Background: Amiodarone is associated with varying degrees of hepatotoxicity. Aims: to
study the association between the presence of the metabolic syndrome or rightsided heart …

The medical records of client‐owned dogs in which amiodarone was used to manage atrial
fibrillation (AF) were reviewed. Data analyzed included signalment, history of heart failure …

For the first time a simple and fast high-performance liquid chromatography (HPLC) method
using a novel sample preparation procedure based on microextraction by packed sorbent …