The yin and yang of ERBB4: tumor suppressor and oncoprotein
ERBB4 (HER4) is a member of the ERBB family of receptor tyrosine kinases, a family that
includes the epidermal growth factor receptor (EGFR/ERBB1/HER1), ERBB2 (Neu/HER2) …
includes the epidermal growth factor receptor (EGFR/ERBB1/HER1), ERBB2 (Neu/HER2) …
[HTML][HTML] The role of MAPK, notch and Wnt signaling pathways in papillary thyroid cancer: Evidence from a systematic review and meta-analyzing microarray datasets …
E Amjad, S Asnaashari, A Jahanban-Esfahlan… - … and Biophysics Reports, 2024 - Elsevier
Papillary thyroid cancer (PTC) is a prevalent kind of thyroid cancer (TC), with the risk of
metastasis increasing faster than any other malignancy. So, understanding the role of PTC …
metastasis increasing faster than any other malignancy. So, understanding the role of PTC …
Comprehensive molecular biomarker identification in breast cancer brain metastases
Background Breast cancer brain metastases (BCBM) develop in about 20–30% of breast
cancer (BC) patients. BCBM are associated with dismal prognosis not at least due to lack of …
cancer (BC) patients. BCBM are associated with dismal prognosis not at least due to lack of …
Systems biomarkers for papillary thyroid cancer prognosis and treatment through multi-omics networks
G Gulfidan, M Soylu, D Demirel, HBC Erdonmez… - Archives of biochemistry …, 2022 - Elsevier
The identification of biomolecules associated with papillary thyroid cancer (PTC) has upmost
importance for the elucidation of the disease mechanism and the development of effective …
importance for the elucidation of the disease mechanism and the development of effective …
Integrated data analysis reveals potential drivers and pathways disrupted by DNA methylation in papillary thyroid carcinomas
CM Beltrami, MB Dos Reis, MC Barros-Filho… - Clinical …, 2017 - Springer
Background Papillary thyroid carcinoma (PTC) is a common endocrine neoplasm with a
recent increase in incidence in many countries. Although PTC has been explored by gene …
recent increase in incidence in many countries. Although PTC has been explored by gene …
Genetic relationship between Hashimotos thyroiditis and papillary thyroid carcinoma with coexisting Hashimotos thyroiditis
O Subhi, HJ Schulten, N Bagatian, R Al-Dayini… - PLoS …, 2020 - journals.plos.org
Hashimoto's thyroiditis (HT) is present in the background of around 30% of papillary thyroid
carcinomas (PTCs). The genetic predisposition effect of this autoimmune condition is not …
carcinomas (PTCs). The genetic predisposition effect of this autoimmune condition is not …
Inhibition of miR-146b expression increases radioiodine-sensitivity in poorly differential thyroid carcinoma via positively regulating NIS expression
L Li, B Lv, B Chen, M Guan, Y Sun, H Li… - Biochemical and …, 2015 - Elsevier
Dedifferentiated thyroid carcinoma (DTC) with the loss of radioiodine uptake (RAIU) is often
observed in clinical practice under radioiodine therapy, indicating the challenge for poor …
observed in clinical practice under radioiodine therapy, indicating the challenge for poor …
Upregulation of the ESR1 Gene and ESR Ratio (ESR1/ESR2) is Associated with a Worse Prognosis in Papillary Thyroid Carcinoma: The Impact of the Estrogen …
Background A gender disparity exists with respect to the incidence of papillary thyroid
cancer (PTC), suggesting that sex hormones such as estrogen play a role in PTC …
cancer (PTC), suggesting that sex hormones such as estrogen play a role in PTC …
Microarray Expression Data Identify DCC as a Candidate Gene for Early Meningioma Progression
HJ Schulten, D Hussein, F Al-Adwani, S Karim… - PloS one, 2016 - journals.plos.org
Meningiomas are the most common primary brain tumors bearing in a minority of cases an
aggressive phenotype. Although meningiomas are stratified according to their histology and …
aggressive phenotype. Although meningiomas are stratified according to their histology and …
[HTML][HTML] Microarray expression profiling identifies genes, including cytokines, and biofunctions, as diapedesis, associated with a brain metastasis from a papillary …
HJ Schulten, D Hussein, F Al-Adwani… - American journal of …, 2016 - ncbi.nlm.nih.gov
Brain metastatic papillary thyroid carcinomas (PTCs) are afflicted with unfavorable
prognosis; however, the underlying molecular genetics of these rare metastases are virtually …
prognosis; however, the underlying molecular genetics of these rare metastases are virtually …