Radiotheranostics global market and future developments

A Al-Ibraheem, R Zimmermann, AS Abdlkadir… - Seminars in Nuclear …, 2024 - Elsevier
Radiotheranostics, a combination of diagnostic and therapeutic approaches, was first
utilized in cancer management using radiopharmaceuticals to both image and selectively …

[HTML][HTML] Posterity of nanoscience as lipid nanosystems for Alzheimer's disease regression

SS Naser, D Singh, S Preetam, S Kishore, L Kumar… - Materials Today Bio, 2023 - Elsevier
Alzheimer's disease (AD) is a type of dementia that affects a vast number of people around
the world, causing a great deal of misery and death. Evidence reveals a relationship …

Indole-Based Compounds in the Development of Anti-Neurodegenerative Agents

E Barresi, E Baglini, V Poggetti, J Castagnoli… - Molecules, 2024 - mdpi.com
Neurodegeneration is a gradual decay process leading to the depletion of neurons in both
the central and peripheral nervous systems, ultimately resulting in cognitive dysfunctions …

Advances in fluorescent probe development for bioimaging of potential Parkinson's biomarkers

X Sun, Q Jiang, Y Zhang, J Su, W Liu, J Lv… - European Journal of …, 2024 - Elsevier
Parkinson's disease (PD) is a common neurodegenerative disease. The clinical symptoms
of PD are usually related to motor symptoms, including postural instability, rigidity …

Structure‐Based Discovery of A Small Molecule Inhibitor of Histone Deacetylase 6 (HDAC6) that Significantly Reduces Alzheimer's Disease Neuropathology

P Mondal, P Bai, A Gomm, G Bakiasi… - Advanced …, 2024 - Wiley Online Library
Abstract Histone deacetylase 6 (HDAC6) is one of the key histone deacetylases (HDACs)
that regulates various cellular functions including clearance of misfolded protein and …

Detection and disaggregation of amyloid fibrils by luminescent amphiphilic platinum (II) complexes

Z Li, AB Ekanayake, AE Bartman, JA Doorn… - Dalton …, 2024 - pubs.rsc.org
Cyclometallated Pt (II) complexes possessing hydrophobic 2-phenylpyridine (ppy) ligands
and hydrophilic acetonylacetone (acac) ligands have been investigated for their ability to …

Recent Advances in Fluorescent Theranostics for Alzheimer's Disease: A Comprehensive Survey on Design, Synthesis, and Properties

TN Francisco, D Malafaia, L Melo, AMS Silva… - ACS …, 2024 - ACS Publications
Alzheimer's disease (AD) is the most common form of neurodegenerative dementia that is
rapidly becoming a major health problem, especially in developed countries because of …

Recent progress of small-molecule-based theranostic agents in Alzheimer's disease

F Gao, J Chen, Y Zhou, L Cheng, M Hu… - RSC Medicinal …, 2023 - pubs.rsc.org
Alzheimer's disease (AD) is the most common forms of neurodegenerative dementia. As a
multifactorial disease, AD involves several etiopathogenic mechanisms, in which multiple …

Isatin-based spiro indolenine alkaloids from Isatis indigotica Fortune with anti-neuroinflammatory and acetylcholinesterase inhibitory effects

M Bai, YF Xi, SH Mi, PY Yang, LL Lou, TM Lv… - Organic Chemistry …, 2024 - pubs.rsc.org
Isatin-based spiro indolenine alkaloids are derived from mixed biosynthetic origins, and the
C-2 and C-3 carbonyl groups of isatin could be spirocyclic, thus achieving a variable …

Aromatic glycosides and lignans glycosides with their acetylcholinesterase inhibitory activities from the leaves of Picrasma quassioides

Q Jia, PY Yang, X Zhang, SJ Song, XX Huang - Fitoterapia, 2024 - Elsevier
In this study, eight new natural products were isolated from the leaves of Picrasma
quassioides. Spectroscopic techniques were used for the elucidation of their planar …