Monoaminergic neuropathology in Alzheimer's disease

G Šimić, MB Leko, S Wray, CR Harrington… - Progress in …, 2017 - Elsevier
None of the proposed mechanisms of Alzheimer's disease (AD) fully explains the distribution
patterns of the neuropathological changes at the cellular and regional levels, and their …

The implication of 5-HT receptor family members in aggression, depression and suicide: similarity and difference

NK Popova, AS Tsybko, VS Naumenko - International journal of molecular …, 2022 - mdpi.com
Being different multifactorial forms of psychopathology, aggression, depression and suicidal
behavior, which is considered to be violent aggression directed against the self, have …

A new three-dimensional model for emotions and monoamine neurotransmitters

H Lövheim - Medical hypotheses, 2012 - Elsevier
The monoamines serotonin, dopamine and noradrenaline have a great impact on mood,
emotion and behavior. This article presents a new three-dimensional model for monoamine …

Neurotransmitter receptors and cognitive dysfunction in Alzheimer's disease and Parkinson's disease

Y Xu, J Yan, P Zhou, J Li, H Gao, Y Xia, Q Wang - Progress in neurobiology, 2012 - Elsevier
Cognitive dysfunction is one of the most typical characteristics in various neurodegenerative
diseases such as Alzheimer's disease and Parkinson's disease (advanced stage). Although …

The serotonergic system in ageing and Alzheimer's disease

JJ Rodríguez, HN Noristani, A Verkhratsky - Progress in neurobiology, 2012 - Elsevier
Alzheimer's disease (AD) is one of the major neurodegenerative diseases that deteriorates
cognitive functions and primarily affects associated brain regions involved in learning and …

Ascending monoaminergic systems alterations in Alzheimer's disease. Translating basic science into clinical care

L Trillo, D Das, W Hsieh, B Medina… - Neuroscience & …, 2013 - Elsevier
Extensive neuropathological studies have established a compelling link between
abnormalities in structure and function of subcortical monoaminergic (MA-ergic) systems …

Brain serotonin transporter density and aggression in abstinent methamphetamine abusers

Y Sekine, Y Ouchi, N Takei, E Yoshikawa… - Archives of general …, 2006 - jamanetwork.com
Context In animals, methamphetamine is known to have a neurotoxic effect on serotonin
neurons, which have been implicated in the regulation of mood, anxiety, and aggression. It …

Behavioral and psychological symptoms in Alzheimer's disease

XL Li, N Hu, MS Tan, JT Yu… - BioMed research …, 2014 - Wiley Online Library
Neuropsychiatric symptoms (NPS) such as depression, apathy, aggression, and psychosis
are now recognized as core features of Alzheimer's disease (AD), and there is a general …

From genes to aggressive behavior: the role of serotonergic system

NK Popova - Bioessays, 2006 - Wiley Online Library
Recent investigations in neurogenomics have opened up new lines of research into a
crucial genetic problem—the pathway from genes to behavior. This paper concentrates on …

[HTML][HTML] Relationships between mitochondrial dysfunction and neurotransmission failure in Alzheimer's disease

KY Wong, J Roy, ML Fung, BC Heng, C Zhang… - Aging and …, 2020 - ncbi.nlm.nih.gov
Besides extracellular deposition of amyloid beta and formation of phosphorylated tau in the
brains of patients with Alzheimer's disease (AD), the pathogenesis of AD is also thought to …