Autoimmune diseases have long been known to share a common pathogenesis involving a
dysregulated immune system with a failure to recognize self from non-self-antigens. This …

The advent of immunotherapy, a groundbreaking advancement in cancer treatment, has
given rise to the prominence of the tumor microenvironment (TME) as a critical area of …

Background Several recent observational studies have reported that gut microbiota
composition is associated with preeclampsia. However, the causal effect of gut microbiota …

Background Previous researches have implicated a vital association between gut microbiota
(GM) and diabetic retinopathy (DR) based on the association of the “gut-retina” axis. But …

Objective: Ankylosing spondylitis (AS) is associated with a variety of gut microbiotas. We aim
to analyze the causal relationship between the two at the genetic level. Methods: Mendelian …

Objective The real causal relationship between human gut microbiota and T1D remains
unclear and difficult to establish. Herein, we adopted a two-sample bidirectional mendelian …

Background Observational studies have demonstrated an association between gut
microbiota and myasthenia gravis; however, the causal relationship between the two still …

Background Growing evidence has suggested that gut microbiota is closely related to the
risk of irritable bowel syndrome (IBS), but whether there is a causal effect remains unknown …

Diabetes and its complications cause a heavy disease burden globally. Identifying
exposures, risk factors and molecular processes causally associated with the development …

Introduction The oral cavity and the gut tract are interconnected, and both contain abundant
natural microbiota. Gut microbiota may interact with oral flora and participate in the …