Efforts to develop anti-cancer therapies have largely focused on targeting the epithelial
compartment, despite the presence of non-neoplastic stromal components that substantially …

In recent years, chronic overnutrition, such as consumption of a high-fat diet (HFD), has
been increasingly viewed as a significant modifiable risk factor for diseases such as …

Inflammatory bowel diseases (IBDs) result in diarrhea and abdominal pain with further
potential complications such as tissue fibrosis and stenosis. Animal models help in …

Crohn's disease (CD) and ulcerative colitis (UC) are both highly inflammatory diseases of
the gastrointestinal tract, collectively known as inflammatory bowel disease (IBD). Although …

Inflammatory bowel diseases (IBD), mainly comprising ulcerative colitis and Crohn's
Disease, are complex and multifactorial diseases with unknown etiology. For the past 20 …

Background & Aims It is not clear how the complex interactions between diet and the
intestinal microbiota affect development of mucosal inflammation or inflammatory bowel …

Inflammatory bowel disease (IBD) is one relapsing and lifelong disease that affects millions
of patients worldwide. Increasing evidence has recently highlighted immune-system …

Ulcerative colitis and Crohn's disease are a set of chronic, idiopathic, immunological and
relapsing inflammatory disorders of the gastrointestinal tract referred to as inflammatory …

Prolonged high fat diets (HFD) induce low-grade chronic intestinal inflammation in mice, and
diets high in saturated fat are a risk factor for the development of human inflammatory bowel …

Gut microbiota play an important part in the pathogenesis of mucosal inflammation, such as
inflammatory bowel disease (IBD). However, owing to the complexity of the gut microbiota …