[HTML][HTML] Roles of the polyphenol–gut microbiota interaction in alleviating colitis and preventing colitis-associated colorectal cancer

Y Zhao, Q Jiang - Advances in Nutrition, 2021 - Elsevier
Accumulating evidence indicates that the gut microbiota can promote or inhibit colonic
inflammation and carcinogenesis. Promotion of beneficial gut bacteria is considered a …

Oral delivery of IL-22 mRNA-loaded lipid nanoparticles targeting the injured intestinal mucosa: A novel therapeutic solution to treat ulcerative colitis

J Sung, Z Alghoul, D Long, C Yang, D Merlin - Biomaterials, 2022 - Elsevier
Oral mRNA delivery is a promising yet understudied approach for treating inflammatory
bowel disease (IBD). Inspired by the colon-targeting ability of ginger-derived nanoparticles …

A slippery slope: On the origin, role and physiology of mucus

F Taherali, F Varum, AW Basit - Advanced drug delivery reviews, 2018 - Elsevier
The mucosa of the gastrointestinal tract, eyes, nose, lungs, cervix and vagina is lined by
epithelium interspersed with mucus-secreting goblet cells, all of which contribute to their …

Animal models of inflammatory bowel disease: a review

N Goyal, A Rana, A Ahlawat, KRV Bijjem… - Inflammopharmacology, 2014 - Springer
Inflammatory bowel disease (IBD) represents a group of idiopathic chronic inflammatory
intestinal conditions associated with various areas of the GI tract, including two types of …

[HTML][HTML] Ulcerative colitis: Gut microbiota, immunopathogenesis and application of natural products in animal models

RP do Nascimento, AP da Fonseca Machado, J Galvez… - Life sciences, 2020 - Elsevier
Ulcerative colitis (UC) is an inflammatory bowel disease with increasing incidence in the
world, especially in developing countries. Although knowledge of its pathogenesis has …

[HTML][HTML] Lactobacillus plantarum L15 Alleviates Colitis by Inhibiting LPS-Mediated NF-κB Activation and Ameliorates DSS-Induced Gut Microbiota Dysbiosis

P Yu, C Ke, J Guo, X Zhang, B Li - Frontiers in Immunology, 2020 - frontiersin.org
Previous studies have suggested that the Lactobacillus plantarum bacteria strain could be
effective in ulcerative colitis (UC) management. However, its effects are strain-specific and …

Anti-inflammatory and immunomodulatory effects of Spirulina platensis in comparison to Dunaliella salina in acetic acid-induced rat experimental colitis

MM Abdel-Daim, SM Farouk, FF Madkour… - Immunopharmacology …, 2015 - Taylor & Francis
Context: Spirulina platensis (SP) is used as a source of protein and vitamin supplement in
humans without any significant side-effects. Dunaliella salina (DS) is also regarded as one …

[HTML][HTML] Mesenchymal (Stem) stromal cells based as new therapeutic alternative in inflammatory bowel disease: basic mechanisms, experimental and clinical …

N Eiro, M Fraile, A González-Jubete… - International journal of …, 2022 - mdpi.com
Inflammatory bowel diseases (IBD) are an example of chronic diseases affecting 40% of the
population, which involved tissue damage and an inflammatory process not satisfactorily …

[HTML][HTML] Evaluation of gastrointestinal leakage in multiple enteric inflammation models in chickens

VA Kuttappan, EA Vicuña, JD Latorre… - Frontiers in Veterinary …, 2015 - frontiersin.org
Enteric inflammation models can help researchers' study methods to improve health and
performance and evaluate various growth promoters and dietary formulations targeted to …

Mucoadhesive chitosan hydrogels as rectal drug delivery vessels to treat ulcerative colitis

J Xu, M Tam, S Samaei, S Lerouge, J Barralet… - Acta biomaterialia, 2017 - Elsevier
Mucoadhesive drug delivery systems stick to mucosal tissues and prolong the local retention
time of drugs. Since the colon is covered by a mucosal layer, mucoadhesive rectal …