[HTML][HTML] Beneficial effects of nutritional supplements on intestinal epithelial barrier functions in experimental colitis models in vivo

H Vargas-Robles, KF Castro-Ochoa… - World Journal of …, 2019 - ncbi.nlm.nih.gov
Acute and chronic colitis affect a huge proportion of the population world-wide. The etiology
of colitis cases can be manifold, and diet can significantly affect onset and outcome of colitis …

Colitis is associated with loss of the histidine phosphatase LHPP and upregulation of histidine phosphorylation in intestinal epithelial cells

M Linder, D Liko, V Kancherla, S Piscuoglio, MN Hall - Biomedicines, 2023 - mdpi.com
Protein histidine phosphorylation (pHis) is a posttranslational modification involved in cell
cycle regulation, ion channel activity and phagocytosis. Using novel monoclonal antibodies …

[HTML][HTML] Longitudinal analysis of inflammation and microbiota dynamics in a model of mild chronic dextran sulfate sodium-induced colitis in mice

L De Fazio, E Cavazza, E Spisni… - World Journal of …, 2014 - ncbi.nlm.nih.gov
AIM: To characterize longitudinally the inflammation and the gut microbiota dynamics in a
mouse model of dextran sulfate sodium (DSS)-induced colitis. METHODS: In animal models …

Arctigenin but not arctiin acts as the major effective constituent of Arctium lappa L. fruit for attenuating colonic inflammatory response induced by dextran sulfate …

X Wu, Y Yang, Y Dou, J Ye, D Bian, Z Wei… - International …, 2014 - Elsevier
The crude powder of the fruit of Arctium lappa L.(ALF) has previously been reported to
attenuate experimental colitis in mice. But, its main effective ingredient and underlying …

[HTML][HTML] Intestinal neuroendocrine cells and goblet cells are mediators of IL-17A-amplified epithelial IL-17C production in human inflammatory bowel disease

M Friedrich, J Diegelmann, J Schauber… - Mucosal …, 2015 - Elsevier
Abstract Interleukin (IL)-17C is a novel member of the IL-17 cytokine family. Its function in
human inflammatory bowel disease (IBD) remains elusive as its role in colonic inflammation …

The inflammasomes, immune guardians at defence barriers

P Palazon‐Riquelme, G Lopez‐Castejon - Immunology, 2018 - Wiley Online Library
As a result of its strategic location, the epithelium is constantly exposed to a wide variety of
pathogen and danger signals. Traditionally, the epithelium has been perceived as a …

Dietary Cannabidiol Activates PKA/AMPK Signaling and Attenuates Chronic Inflammation and Leaky Gut in DSS‐Induced Colitis Mice

Q Sun, A Bravo Iniguez, Q Tian, M Du… - Molecular Nutrition & …, 2024 - Wiley Online Library
Scope Inflammatory bowel disease (IBD) is characterized by chronic inflammation in the gut,
accompanied by impaired epithelial integrity, increased macrophage infiltration, and …

[HTML][HTML] Poultry enteric inflammation model with dextran sodium sulfate mediated chemical induction and feed restriction in broilers

VA Kuttappan, LR Berghman, EA Vicuña, JD Latorre… - Poultry Science, 2015 - Elsevier
Gut inflammation is a cardinal event occurring in various gastrointestinal diseases
regardless of etiology. A potential mechanism of action for antibiotic growth promoters and …

Green tea EGCG effectively alleviates experimental colitis in middle-aged male mice by attenuating multiple aspects of oxi-inflammatory stress and cell cycle …

B Diwan, R Sharma - Biogerontology, 2022 - Springer
Age-dependent increased risk of inflammatory bowel diseases such as ulcerative colitis is
being increasingly realized, and yet therapies targeting this disorder within the purview of …

ARF1 maintains intestinal homeostasis by modulating gut microbiota and stem cell function

D Yu, Q Dai, Z Wang, SX Hou, LV Sun - Life Sciences, 2023 - Elsevier
Abstract Aims The small GTPase protein ARF1 has been shown to be involved in the
lipolysis pathway and to selectively kill stem cells in Drosophila melanogaster. However, the …