Design, synthesis and biological evaluation of a new series of arylidene indanones as small molecules for targeted therapy of non-small cell lung carcinoma and …
MD Altıntop, A Özdemir, HE Temel… - European Journal of …, 2022 - Elsevier
In an attempt to identify small molecules for targeted therapy of non-small cell lung
carcinoma (NSCLC) and prostate cancer (PCa), new arylidene indanones (1–10) were …
carcinoma (NSCLC) and prostate cancer (PCa), new arylidene indanones (1–10) were …
Design, synthesis and biological evaluation of a new series of imidazothiazole-hydrazone hybrids as dual EGFR and Akt inhibitors for NSCLC therapy
In search of small molecules for targeted therapy of non-small cell lung carcinoma (NSCLC),
an efficient four-step synthetic route was followed for the synthesis of new imidazothiazole …
an efficient four-step synthetic route was followed for the synthesis of new imidazothiazole …
The Role and Efficacy of JNK Inhibition in Inducing Lung Cancer Cell Death Depend on the Concentration of Cisplatin
A Stulpinas, M Tenkutytė, A Imbrasaitė… - ACS …, 2024 - ACS Publications
Toxicity and the emergence of resistance are the main challenges in cancer treatment. The
optimal dose of cisplatin, one of the most widely used chemotherapeutic anticancer drugs, is …
optimal dose of cisplatin, one of the most widely used chemotherapeutic anticancer drugs, is …
[HTML][HTML] Long noncoding RNA POU6F2-AS2 contributes to the aggressiveness of nonsmall-cell lung cancer via microRNA-125b-5p-mediated E2F3 upregulation
H Yang, X Feng, X Tong - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
The role of the majority of long noncoding RNAs (lncRNAs) in the progression of nonsmall-
cell lung cancer (NSCLC) remains elusive, despite their potential value, thus warranting in …
cell lung cancer (NSCLC) remains elusive, despite their potential value, thus warranting in …
Design, synthesis, and evaluation of a new series of hydrazones as small-molecule akt inhibitors for NSCLC therapy
B Erdönmez, MD Altıntop, G Akalın Çiftçi… - ACS …, 2023 - ACS Publications
In an endeavor to identify small molecules for the management of non-small-cell lung
carcinoma, 10 new hydrazone derivatives (3a–j) were synthesized. MTT test was conducted …
carcinoma, 10 new hydrazone derivatives (3a–j) were synthesized. MTT test was conducted …
Design, synthesis and anticancer activity of β-carboline based pseudo-natural products by inhibiting AKT/mTOR signaling pathway
L Lv, K Song, Y Xiao, J Zheng, W Zhang, L Li, Y Wei… - Bioorganic …, 2024 - Elsevier
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer and remains
the leading cause of cancer deaths. Much progress has been made to treat NSCLC …
the leading cause of cancer deaths. Much progress has been made to treat NSCLC …
Association of COVID-19 and Lung Cancer: Short-Term and Long-Term Interactions
YL Peng, ZY Wang, RW Zhong, SQ Mei, JQ Liu… - Cancers, 2024 - mdpi.com
Simple Summary Since 2019, COVID-19 has had major effects around the world. Lung
cancer and COVID-19 are both diseases of the respiratory system, and it is interesting to …
cancer and COVID-19 are both diseases of the respiratory system, and it is interesting to …
Investigating the determinants of fear of cancer recurrence in patients with early‐stage non‐small cell lung cancer: Insights from a restricted cubic spline model
M Liu, L Liu, Z Lv, Y Mao, Y Liu - Cancer Medicine, 2024 - Wiley Online Library
Objective This study aims to investigate the determinants and the dose–response
relationship of fear of cancer recurrence among patients with early‐stage non‐small cell …
relationship of fear of cancer recurrence among patients with early‐stage non‐small cell …
Discovery of small molecule COX-1 and Akt inhibitors as anti-NSCLC agents endowed with anti-inflammatory action
MD Altıntop, G Akalın Çiftçi, N Yılmaz Savaş… - International Journal of …, 2023 - mdpi.com
Targeted therapies have come into prominence in the ongoing battle against non-small cell
lung cancer (NSCLC) because of the shortcomings of traditional chemotherapy. In this …
lung cancer (NSCLC) because of the shortcomings of traditional chemotherapy. In this …
The role of immunotherapy in lung cancer: Actual scenery
I Ertorun, A Huseynli, SN Ertekın… - European Journal of Life …, 2023 - dergipark.org.tr
More than half of those who succumb to cancer each year also lose their battle with the
disease, making cancer a leading cause of death worldwide. After surgery, hormonal …
disease, making cancer a leading cause of death worldwide. After surgery, hormonal …