Tendon is an intricately organized connective tissue that efficiently transfers muscle force to
the bony skeleton. Its structure, function, and physiology reflect the extreme, repetitive …

Cardiac and skeletal striated muscles are intricately designed machines responsible for
muscle contraction. Coordination of the basic contractile unit, the sarcomere, and the …

While the majority of cells contain a single nucleus, cell types such as trophoblasts,
osteoclasts, and skeletal myofibers require multinucleation. One advantage of …

Cell‐laden hydrogels used in tissue engineering generally lack sufficient 3D topographical
guidance for cells to mature into aligned tissues. A new strategy called filamented light …

Syncytial skeletal muscle cells contain hundreds of nuclei in a shared cytoplasm. We
investigated nuclear heterogeneity and transcriptional dynamics in the uninjured and …

Traumatic muscle injury represents a collection of skeletal muscle pathologies caused by
trauma to the muscle tissue and is defined as damage to the muscle tissue that can result in …

Engineering synthetic scaffolds to repair and regenerate ruptured native tendon and
ligament (T/L) tissues is a significant engineering challenge due to the need to satisfy both …

Tendon and ligament (TL) injuries affect millions of people annually. Biopolymers play a
significant role in TL tissue repair, whether the treatment relies on tissue engineering …

Tissue engineering is a promising approach to repair tendon and muscle when natural
healing fails. Biohybrid constructs obtained after cells' seeding and culture in dedicated …

While the importance of RNA localization in highly differentiated cells is well appreciated,
basic principles of RNA localization in skeletal muscle remain poorly characterized. Here …