[HTML][HTML] Lipid nanoparticles for delivery of RNA therapeutics: Current status and the role of in vivo imaging
Lipid nanoparticles (LNPs) have been one of the most successful nano-delivery vehicles
that enable efficient delivery of cytotoxic chemotherapy agents, antibiotics, and nucleic acid …
that enable efficient delivery of cytotoxic chemotherapy agents, antibiotics, and nucleic acid …
Recent progress in bioconjugation strategies for liposome-mediated drug delivery
In nanoparticle (NP)-mediated drug delivery, liposomes are the most widely used drug
carrier, and the only NP system currently approved by the FDA for clinical use, owing to their …
carrier, and the only NP system currently approved by the FDA for clinical use, owing to their …
Scalable mRNA and siRNA lipid nanoparticle production using a parallelized microfluidic device
A major challenge to advance lipid nanoparticles (LNPs) for RNA therapeutics is the
development of formulations that can be produced reliably across the various scales of drug …
development of formulations that can be produced reliably across the various scales of drug …
Inhibition of nonalcoholic fatty liver disease in mice by selective inhibition of mTORC1
Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) remain
without effective therapies. The mechanistic target of rapamycin complex 1 (mTORC1) …
without effective therapies. The mechanistic target of rapamycin complex 1 (mTORC1) …
The mRNA vaccine revolution: COVID-19 has launched the future of vaccinology
During the COVID-19 pandemic, mRNA (mRNA) vaccines emerged as leading vaccine
candidates in a record time. Nonreplicating mRNA (NRM) and self-amplifying mRNA (SAM) …
candidates in a record time. Nonreplicating mRNA (NRM) and self-amplifying mRNA (SAM) …
[HTML][HTML] Nanotechnology advances in the detection and treatment of cancer: an overview
Over the last few years, progress has been made across the nanomedicine landscape, in
particular, the invention of contemporary nanostructures for cancer diagnosis and …
particular, the invention of contemporary nanostructures for cancer diagnosis and …
[HTML][HTML] Gene therapy in cancer treatment: why go nano?
The proposal of gene therapy to tackle cancer development has been instrumental for the
development of novel approaches and strategies to fight this disease, but the efficacy of the …
development of novel approaches and strategies to fight this disease, but the efficacy of the …
[HTML][HTML] Recent advances in nanocarrier-assisted therapeutics delivery systems
S Su, PM Kang - Pharmaceutics, 2020 - mdpi.com
Nanotechnologies have attracted increasing attention in their application in medicine,
especially in the development of new drug delivery systems. With the help of nano-sized …
especially in the development of new drug delivery systems. With the help of nano-sized …
[HTML][HTML] Recent advances in using liposomes for delivery of nucleic acid-based therapeutics
Nucleic acid therapeutics are rapidly expanding because of recent advancements in
production and purification. This class of therapeutics may change the field of disease …
production and purification. This class of therapeutics may change the field of disease …
Nanocarrier vaccines for SARS-CoV-2
The SARS-CoV-2 global pandemic has seen rapid spread, disease morbidities and death
associated with substantive social, economic and societal impacts. Treatments rely on re …
associated with substantive social, economic and societal impacts. Treatments rely on re …