Design of biocompatible dendrimers for cancer diagnosis and therapy: current status and future perspectives

Y Cheng, L Zhao, Y Li, T Xu - Chemical Society Reviews, 2011 - pubs.rsc.org
In the past decade, nanomedicine with its promise of improved therapy and diagnostics has
revolutionized conventional health care and medical technology. Dendrimers and dendrimer …

Theoretical and computational studies of dendrimers as delivery vectors

Y Ma - Chemical Society Reviews, 2013 - pubs.rsc.org
It is a great challenge for nanomedicine to develop novel dendrimers with maximum
therapeutic potential and minimum side-effects for drug and gene delivery. As delivery …

NMR insights into dendrimer-based host–guest systems

J Hu, T Xu, Y Cheng - Chemical reviews, 2012 - ACS Publications
1. INTRODUCTION The host− guest chemistry was first developed with the discovery of
crown ethers by Pederson in the 1960s. 1, 2 It was found that the cyclic crown ethers are …

Dendritic effects: dependency of dendritic nano-periodic property patterns on critical nanoscale design parameters (CNDPs)

DA Tomalia - New Journal of Chemistry, 2012 - pubs.rsc.org
The term dendritic effects has been used extensively by many dendritic polymer scientists
since the early 1990s to describe certain intrinsic physico-chemical and application property …

Association of chemotherapeutic drugs with dendrimer nanocarriers: an assessment of the merits of covalent conjugation compared to noncovalent encapsulation

LM Kaminskas, VM McLeod, CJH Porter… - Molecular …, 2012 - ACS Publications
Cancer is a leading cause of death within developed nations, and part of this morbidity is
due to difficulties associated with its treatment. Currently, anticancer therapy relies heavily …

Impact of grape pectic polysaccharides on anthocyanins thermostability

A Fernandes, E Brandão, F Raposo, É Maricato… - Carbohydrate …, 2020 - Elsevier
The impact of grape pectic polysaccharides on malvidin-3-O-β-d-glucoside thermostability
was evaluated in model solutions. Pectic polysaccharides richer in homogalacturonan …

Immunosuppressive and anti‐inflammatory properties of engineered nanomaterials

AN Ilinskaya, MA Dobrovolskaia - British journal of …, 2014 - Wiley Online Library
Nanoparticle interactions with various components of the immune system are determined by
their physicochemical properties such as size, charge, hydrophobicity and shape …

Dendrimers and miktoarm polymers based multivalent nanocarriers for efficient and targeted drug delivery

GM Soliman, A Sharma, D Maysinger… - Chemical …, 2011 - pubs.rsc.org
The delivery of biologically active agents to the desired site in the body and intracellular
organelles is still a big challenge despite efforts made for more than five decades. With the …

Dendrimer–doxorubicin conjugate for enhanced therapeutic effects for cancer

S Chandra, S Dietrich, H Lang… - Journal of Materials …, 2011 - pubs.rsc.org
An oligo (ethylene glycol)-grafted amidoamine dendrimer was synthesized and
characterized by FTIR, MS, 1H and 13C NMR. The dendritic scaffold was evaluated for its …

Poly (amido amine) dendrimers as absorption enhancers for oral delivery of camptothecin

S Sadekar, G Thiagarajan, K Bartlett, D Hubbard… - International journal of …, 2013 - Elsevier
Oral delivery of camptothecin has a treatment advantage but is limited by low bioavailability
and gastrointestinal toxicity. Poly (amido amine) or PAMAM dendrimers have shown …