[HTML][HTML] Reactive oxygen species (ROS) in cancer pathogenesis and therapy: An update on the role of ROS in anticancer action of benzophenanthridine alkaloids

AQ Khan, K Rashid, AA AlAmodi, MV Agha… - Biomedicine & …, 2021 - Elsevier
Reactive oxygen species play crucial role in biological homeostasis and pathogenesis of
human diseases including cancer. In this line, now it has become evident that ROS …

Natural isoquinoline alkaloids: Pharmacological features and multi-target potential for complex diseases

E Plazas, DR Muñoz - Pharmacological Research, 2022 - Elsevier
Complex diseases such as neurodegenerative disorders and cancer constitute a growing
public health problem due to the rising incidence and lack in effective therapies. Since …

[HTML][HTML] An update of the sanguinarine and benzophenanthridine alkaloids' biosynthesis and their applications

JI Laines-Hidalgo, JA Muñoz-Sánchez, L Loza-Müller… - Molecules, 2022 - mdpi.com
Benzophenanthridines belong to the benzylisoquinolic alkaloids, representing one of the
main groups of this class. These alkaloids include over 120 different compounds, mostly in …

[HTML][HTML] Endophytic fungi residing in medicinal plants have the ability to produce the same or similar pharmacologically active secondary metabolites as their hosts

A Venieraki, M Dimou, P Katinakis - Hellenic Plant Protection Journal, 2017 - sciendo.com
Medicinal plants have been used for thousands of years in folk medicines and still are used
for their health benefits. In our days medicinal plants are exploited for the isolation of plant …

[HTML][HTML] Alkaloids: therapeutic potential against human coronaviruses

BC Fielding, C da Silva Maia Bezerra Filho, NSM Ismail… - Molecules, 2020 - mdpi.com
Alkaloids are a class of natural products known to have wide pharmacological activity and
have great potential for the development of new drugs to treat a wide array of pathologies …

Diverse alkaloids and biological activities of Fumaria (Papaveraceae): An ethnomedicinal group

R Zhang, Q Guo, EJ Kennelly, C Long, X Chai - Fitoterapia, 2020 - Elsevier
Fumaria species, commonly known as fumitory or earth smoke, are considered weeds in
many regions. However, several Fumaria species have long been used in folk medicine …

[HTML][HTML] Antibiofilm and antimicrobial-enhancing activity of Chelidonium majus and Corydalis cheilanthifolia extracts against multidrug-resistant Helicobacter pylori

P Krzyżek, A Junka, W Słupski, A Dołowacka-Jóźwiak… - Pathogens, 2021 - mdpi.com
Pathogens | Free Full-Text | Antibiofilm and Antimicrobial-Enhancing Activity of Chelidonium
majus and Corydalis cheilanthifolia Extracts against Multidrug-Resistant Helicobacter pylori …

[HTML][HTML] Targeting natural products against SARS-CoV-2

A Al-Harrasi, T Behl, T Upadhyay, S Chigurupati… - … Science and Pollution …, 2022 - Springer
The human coronavirus disease (COVID-19) pandemic is caused by a novel coronavirus;
the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2). Natural products …

6-methoxydihydroavicine, the alkaloid extracted from Macleaya cordata (Willd.) R. Br.(Papaveraceae), triggers RIPK1/Caspase-dependent cell death in pancreatic …

N Ma, F Shangguan, H Zhou, H Huang, J Lei, J An… - Phytomedicine, 2022 - Elsevier
Background Many extracts and purified alkaloids of M. cordata (Papaveraceae family) have
been reported to display promising anti-tumor effects by inhibiting cancer cell growth and …

Two Pairs of Enantiomeric Alkaloid Dimers from Macleaya cordata

CM Sai, DH Li, CM Xue, KB Wang, P Hu, YH Pei… - Organic …, 2015 - ACS Publications
Two pairs of enantiomeric alkaloid dimers,(±)-macleayins A (1) and B (2), representing a
novel dimerization pattern of two different types of alkaloids via a C–C σ-bond, were isolated …