Senescence is a cellular aging process in all multicellular organisms. It is characterized by a
decay in cellular functions and proliferation, resulting in increased cellular damage and …

Ferroptosis, a unique modality of cell death with mechanistic and morphological differences
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …

Ischemic stroke (IS) has complex pathological mechanisms, and is extremely difficult to treat.
At present, the treatment of IS is mainly based on intravenous thrombolysis and mechanical …

Acute kidney injury (AKI) is a major health concern owing to its high morbidity and mortality
rates, to which there are no drugs or treatment methods, except for renal replacement …

Ischemic stroke (IS) is one of the leading causes of death and disability. Its pathogenesis is
not completely clear, and inflammatory cascade is one of its main pathological processes …

Salvia miltiorrhiza (SM) has been used in oriental medicine for its neuroprotective effects
against cardiovascular diseases and ischemic stroke. In this study, we investigated the …

Acute myocardial infarction remains the leading cause of death in humans. Timely
restoration of blood perfusion to ischemic myocardium remains the most effective strategy in …

Enriched environment (EE) has been proven to be an effective intervention strategy which
can improve neurofunctional recovery following cerebral ischemia/reperfusion (I/R) injury …

Schizandrin B (SchB) protects against oxidative, inflammatory, and ferroptotic injury.
Oxidative stress and inflammation are indispensably involved in nephrolithiasis and …

Dietary lutein can be naturally metabolized to 3′-epilutein and 3′-oxolutein in the human
body. The epimerization of lutein can happen in acidic pH, and through cooking, 3 …