Classic and new markers in diagnostics and classification of breast cancer

R Beňačka, D Szabóová, Z Guľašová, Z Hertelyová… - Cancers, 2022 - mdpi.com
Simple Summary With ever-increasing incidence, breast cancer is considered a most
diagnosed type of cancer among women worldwide. Breast cancer arises through malignant …

Luminal a breast cancer and molecular assays: a review

JJ Gao, SM Swain - The oncologist, 2018 - academic.oup.com
Purpose Chemotherapy has been the historical mainstay of treatment for patients with breast
cancer, with immunohistochemical markers and tumor characteristics driving treatment …

miRpower: a web-tool to validate survival-associated miRNAs utilizing expression data from 2178 breast cancer patients

A Lánczky, Á Nagy, G Bottai, G Munkácsy… - Breast cancer research …, 2016 - Springer
Purpose The proper validation of prognostic biomarkers is an important clinical issue in
breast cancer research. MicroRNAs (miRNAs) have emerged as a new class of promising …

A tRNA fragment, 5′-tiRNAVal, suppresses the Wnt/β-catenin signaling pathway by targeting FZD3 in breast cancer

D Mo, P Jiang, Y Yang, X Mao, X Tan, X Tang, D Wei… - Cancer letters, 2019 - Elsevier
Abstract tRNA-derived fragments offer a recently identified group of non-coding single-
stranded RNAs that are often as abundant as microRNAs in cancer cells and play important …

Molecular classification of breast cancer: what the pathologist needs to know

EA Rakha, AR Green - Pathology, 2017 - Elsevier
Breast cancer is a heterogeneous disease featuring distinct histological, molecular and
clinical phenotypes. Although traditional classification systems utilising clinicopathological …

[HTML][HTML] Breast cancers, mammary stem cells, and cancer stem cells, characteristics, and hypotheses

S Taurin, H Alkhalifa - Neoplasia, 2020 - Elsevier
The cellular heterogeneity of breast cancers still represents a major therapeutic challenge.
The latest genomic studies have classified breast cancers in distinct clusters to inform the …

Long non-coding RNA ANRIL promotes carcinogenesis via sponging miR-199a in triple-negative breast cancer

ST Xu, JH Xu, ZR Zheng, QQ Zhao, XS Zeng… - Biomedicine & …, 2017 - Elsevier
Triple-negative breast cancer (TNBC) is a complex breast cancer subtype characterized by
the absence of estrogen receptor (ER), progesterone receptor (PR) and human epidermal …

New advances in molecular breast cancer pathology

EA Rakha, FG Pareja - Seminars in cancer biology, 2021 - Elsevier
Breast cancer (BC) comprises a diverse spectrum of diseases featuring distinct presentation,
morphological, biological, and clinical phenotypes. BC behaviour and response to therapy …

Nexus between PI3K/AKT and estrogen receptor signaling in breast cancer

AS Khatpe, AK Adebayo, CA Herodotou, B Kumar… - Cancers, 2021 - mdpi.com
Simple Summary Breast cancers are broadly classified into two subtypes: estrogen receptor-
positive and estrogen receptor-negative. Approximately 70% of breast cancers are estrogen …

[HTML][HTML] A tRNA fragment, tRF5-Glu, regulates BCAR3 expression and proliferation in ovarian cancer cells

K Zhou, KW Diebel, J Holy, A Skildum, E Odean… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Ovarian cancer is a complex disease marked by tumor heterogeneity, which contributes to
difficulties in diagnosis and treatment. New molecular targets and better molecular profiles …