[HTML][HTML] Mendelian Randomization Analyses of Chronic Immune-Mediated Diseases, Circulating Inflammatory Biomarkers, and Cytokines in Relation to Liver Cancer

Q Yin, Q Yang, W Shi, UD Kahlert, Z Li, S Lin, Q Song… - Cancers, 2023 - mdpi.com
Simple Summary Liver cancer is a prevalent gastrointestinal carcinoma and is closely linked
to chronic inflammation, including both hepatic and extrahepatic inflammations. However …

Exploring causal correlations between inflammatory cytokines and knee osteoarthritis: a two-sample Mendelian randomization

J Zhang, K Li, X Qiu - Frontiers in Immunology, 2024 - frontiersin.org
Objectives Knee osteoarthritis (KOA) and certain inflammatory cytokines (such as interleukin
1 [IL-1] and tumor necrosis factor alpha [TNF-a]) are related; however, the causal …

[HTML][HTML] Inflammatory cytokines and oral lichen planus: a Mendelian randomization study

X Chen, S Zhang, X Wu, Y Lei, B Lei… - Frontiers in …, 2024 - frontiersin.org
Background Inflammatory cytokines have long been considered closely related to the
development of oral lichen planus (OLP), and we further explored the causal relationship …

[HTML][HTML] Exploring the causal relationship between inflammatory cytokines and inflammatory arthritis: a Mendelian randomization study

S Pan, S Wu, Y Wei, J Liu, C Zhou, T Chen, J Zhu… - Cytokine, 2024 - Elsevier
Objectives Previous studies have reported an association between inflammatory cytokines
and inflammatory arthritis, including Ankylosing spondylitis (AS), rheumatoid arthritis (RA) …

[HTML][HTML] Unraveling the causal role of immune cells in gastrointestinal tract cancers: insights from a Mendelian randomization study

Y Wang, C Zhou, D Wang, J Ma, X Sun… - Frontiers in …, 2024 - frontiersin.org
Background Despite early attempts, the relationship between immune characteristics and
gastrointestinal tract cancers remains incompletely elucidated. Hence, rigorous and further …

[HTML][HTML] Inflammatory cytokines and stroke and its subtypes: a genetic correlation and two-sample Mendelian randomization study

Y Guo, H Sun, S Hou, W Zhang, H Liu… - Frontiers in Molecular …, 2023 - ncbi.nlm.nih.gov
Methods We performed a two-sample MR analysis to assess the causal effects of 41
inflammatory cytokines on stroke and its subtypes and conducted a genome-wide …

[PDF][PDF] Evidence from Mendelian randomization: increased risk of miscarriage in patients with asthma.

YS Xu, RY Liao, D Huang, D Wang… - European Review for …, 2023 - europeanreview.org
OBJECTIVE: Several observational studies have revealed a possible association between
asthma and miscarriage. However, inferring causal relationships from observational studies …

Effect of coffee, tea and alcohol intake on circulating inflammatory cytokines: a two sample-Mendelian randomization study

Y He, S Zhu, Y Zhang, CP Tan, J Zhang… - European journal of …, 2024 - nature.com
Background Despite the abundance of research examining the effects of coffee, tea, and
alcohol on inflammatory diseases, there is a notable absence of conclusive evidence …

Concomitant use of interleukin-2 and tacrolimus suppresses follicular helper T cell proportion and exerts therapeutic effect against lupus nephritis in systemic lupus …

Y Nasa, A Satake, R Tsuji, R Saito… - Frontiers in …, 2024 - frontiersin.org
Introduction Defective interleukin-2 (IL-2) production contributes to immune system
imbalance in patients with systemic erythematosus lupus (SLE). Recent clinical studies …

[HTML][HTML] Potential Causal Association between Plasma Metabolites, Immunophenotypes, and Female Reproductive Disorders: A Two-Sample Mendelian …

HH Shen, YY Zhang, XY Wang, CJ Wang, Y Wang… - Biomolecules, 2024 - mdpi.com
Background: While extensive research highlighted the involvement of metabolism and
immune cells in female reproductive diseases, causality remains unestablished. Methods …