Genetically predicted associations between circulating cytokines and autoimmune diseases: a bidirectional two-sample Mendelian randomization

J Jie, Y Gong, S Luo, X Yang, K Guo - Frontiers in Immunology, 2024 - frontiersin.org
Objectives Previous studies have indicated a correlation between cytokines and
autoimmune diseases. yet the causality remains uncertain. Through Mendelian …

Elucidating the causal nexus between antibody-mediated immunity and autoimmune diseases: Insights from bidirectional mendelian randomization, gene expression …

J Chen, C Wei, S Huang, S Wu, R He, T Chen… - International …, 2024 - Elsevier
Objective This study aimed to elucidate the causal relationships between antibodies and
autoimmune diseases using Mendelian randomization (MR). Methods Data on 46 …

Association between copper intake and essential hypertension: dual evidence from Mendelian randomization analysis and the NHANES database

Q Miao, J Zhang, Y Yun, W Wu, C Luo - Frontiers in Nutrition, 2024 - frontiersin.org
Background Although previous studies have identified an association between trace
elements and essential hypertension, the specific trace elements involved and the …

The causal relationship between gut microbiota and alopecia areata: a Mendelian randomization analysis

D Bi, JT Tey, D Yao, Y Cao, M Qian, J Shi… - Frontiers in …, 2024 - frontiersin.org
Background Increasing evidence suggests a robust correlation between the gut microbiome
and alopecia areata. In light of the extensive diversity of gut microbiota, this study aims to …

The interplay between systemic inflammatory factors and endometriosis: A bidirectional mendelian randomization study

L Wei, S Wang, S Xu, C Zhang - Journal of Reproductive Immunology, 2024 - Elsevier
Objective To utilize vast genetic data to reveal the interplay between 41 systemic
inflammatory factors and endometriosis. Design Bidirectional Mendelian randomization …

Causal relationships between systemic inflammatory cytokines and adhesive capsulitis: a bidirectional Mendelian randomization study

Y Ouyang, M Dai - Frontiers in Immunology, 2024 - frontiersin.org
Background Mounting evidence suggests a connection between inflammatory cytokines and
adhesive capsulitis (AC). However, the specific systemic inflammatory cytokines contributing …

Causal Relationships Between Circulating Inflammatory Proteins and Obstructive Sleep Apnea: A Bidirectional Mendelian Randomization Study

Z Chen, J Zeng, X Pei, J Zhao, F Zhao… - Nature and Science …, 2024 - Taylor & Francis
Purpose Clinical studies have demonstrated the intricate association between the onset and
progression of obstructive sleep apnea (OSA) and the activation of the inflammatory …

Causal role of myeloid cells in Parkinson's disease: Mendelian randomization study

W Quan, Y Qin, J Li, L Wang, J Song, J Xu… - Inflammation …, 2024 - Springer
Background Previous studies have observed elevated myeloid cells in the peripheral blood
of patients with Parkinson's disease (PD), but the causal relationship between them remains …

Associations of the circulating levels of cytokines with risk of ankylosing spondylitis: a Mendelian randomization study

Y Ye, C Wang, R Zhong, X Xiong - Frontiers in Immunology, 2023 - frontiersin.org
Background Observational studies have shown that changes in circulating cytokine/growth
factor levels occur throughout the initiation and progression of ankylosing spondylitis (AS) …

Assessing the Causal Relationship between Genetically Determined Inflammatory Cytokines and Parkinson's Disease Risk: A Bidirectional Two‐Sample Mendelian …

H Xue, Q Luo, J Chen, W Fan - Journal of Immunology …, 2024 - Wiley Online Library
Background. Observational studies have suggested an association between inflammatory
cytokines and Parkinson's disease (PD). This Mendelian randomization (MR) was …