Heart failure (HF) is an important cardiovascular disease because of its increasing
prevalence, significant morbidity, high mortality, and rapidly expanding health care cost. The …

Oxidative stress (OS) is mediated by reactive oxygen species (ROS), which in
cardiovascular and other disease states, damage DNA, lipids, proteins, other cellular and …

Background Hypertrophic cardiomyopathy (HCM) is a prevalent and complex cardiovascular
condition. Despite being strongly associated with genetic alterations, wide variation of …

Heritable cardiomyopathies are a class of heart diseases caused by variations in a number
of genetic loci. Genetic variants on one allele lead to either a degraded protein, which …

Heart failure (HF) with preserved ejection fraction (HFpEF) is an increasingly frequent form
and is estimated to be the dominant form of HF. On the other hand, HFpEF is a syndrome …

Heart failure (HF) with preserved ejection fraction (HFpEF) is a multi-organ, systemic
syndrome that involves multiple cardiac and extracardiac pathophysiologic abnormalities …

Hypertrophic cardiomyopathy (HCM) is a prevalent and complex cardiovascular disease
where cardiac dysfunction often associates with mutations in sarcomeric genes. Various …

The term myocardial contractility is thought to have originated more than 125 years ago and
has remained and enigma ever since. Although the term is frequently used in textbooks …

Heart failure (HF) is a major public health problem in the United States as well as worldwide.
Chronic heart failure is a syndrome of reduced cardiac output resulting from impaired …

Despite recent advances in chronic heart failure management (either pharmacological or
non-pharmacological), the prognosis of heart failure (HF) patients remains poor. This poor …