Body size, physical activity, early-Life energy restriction, and associations with methylated insulin-like growth factor–binding protein genes in colorectal cancer

CCJM Simons, PA van den Brandt… - … Biomarkers & Prevention, 2014 - AACR
Background: We investigated body size, physical activity, and early-life energy restriction in
relation to colorectal tumors with and without methylated insulin-like growth factor–binding …

[HTML][HTML] Unique characteristics of CpG island methylator phenotype (CIMP) in a Chinese population with colorectal cancer

J Liu, L Tang, J Yi, G Li, Y Lu, Y Xu, S Zhao, R Mao… - BMC …, 2019 - Springer
Abstract Background Molecular characteristics of CpG island methylator phenotype (CIMP)
in colorectal cancer (CRC) have been well documented in Western, but not in Chinese …

Commentary: lifestyle factors and colorectal cancer microsatellite instability—molecular pathological epidemiology science, based on unique tumour principle

S Ogino, E Giovannucci - International journal of epidemiology, 2012 - academic.oup.com
Colorectal cancer encompasses fundamentally heterogeneous multifactorial diseases, 1–3
as do breast, lung and other common cancers. Each tumour is unique in terms of the tumour …

[HTML][HTML] LINE-1 hypomethylation in normal colon mucosa is associated with poor survival in Chinese patients with sporadic colon cancer

C Zhuo, Q Li, Y Wu, Y Li, J Nie, D Li, J Peng, P Lian… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Genetic and epigenetic pathways are not independent in colorectal cancer (CRC)
carcinogenesis. We aimed to determine the influence of various molecular features on …

Association between risk factors, molecular features and CpG island methylator phenotype colorectal cancer among different age groups in a Taiwanese cohort

KH Chen, LI Lin, CT Yuan, LH Tseng, YL Chao… - British Journal of …, 2021 - nature.com
Background CpG island methylator phenotype (CIMP) represents a carcinogenesis pathway
of colorectal cancer (CRC) and the association between CIMP CRC, molecular features and …

[HTML][HTML] 结直肠癌CpG 岛甲基化表型的研究进展

矣金华, 刘江, 王昆华 - 世界华人消化杂志, 2016 - wjgnet.com
结直肠癌(colorectal cancer, CRC) 是常见的恶性肿瘤之一, 是由遗传学和表观遗传学改变逐渐
积累导致的. 随着一类被称为" CpG 岛甲基化表型(CpG island methylator phenotype, CIMP)" …

[HTML][HTML] Body shape and pants size as surrogate measures of obesity among males in epidemiologic studies

E Vallières, MH Roy-Gagnon, MÉ Parent - Preventive Medicine Reports, 2020 - Elsevier
This study aimed at characterizing anthropometric indicators that can be used as
alternatives to measurements for assessing overall obesity over adulthood and abdominal …

Site-specific colorectal cancer; how is it different?

HS Kim - The Korean Journal of Gastroenterology, 2013 - synapse.koreamed.org
One of the most critical characteristics of colorectal cancer (CRC) is the difference between
proximal (right-sided colon cancer, RCC) and distal (left-sided colon cancer, LCC) disease …

[HTML][HTML] Investigation of sirtuin 1 polymorphisms in relation to the risk of colorectal cancer by molecular subtype

R Hrzic, CCJM Simons, LJ Schouten… - Scientific Reports, 2020 - nature.com
Abstract Sirtuin 1 (SIRT1), a histone deacetylase, is involved in maintenance of genetic
stability, inflammation, immune response, metabolism (energy-sensing molecule) and …

Ogino et al. respond to “The 21st century epidemiologist”

S Ogino, AH Beck, EE King, ME Sherman… - American journal of …, 2012 - academic.oup.com
MPE is based on the concept that tumors or diseases that are usually lumped together as a
single entity consist of a heterogeneous group of conditions (3). MPE subcategorizes …