Fungal infections represent a major, albeit neglected, public health threat with serious
medical and economic burdens globally. With unacceptably high mortality rates, invasive …

The zebrafish has become a widely accepted model host for studies of infectious disease,
including fungal infections. The species is genetically tractable, and the larvae are …

Cryptococcus neoformans is an opportunistic fungal pathogen that causes
meningoencephalitis. Its cell wall is composed of glucans, proteins, chitin, and chitosan …

Amoeboid predators, such as amoebae, are proposed to select for survival traits in soil
microbes such as Cryptococcus neoformans; these traits can also function in animal …

The fungal pathogen Cryptococcus neoformans causes approximately one million cases of
cryptococcosis per year in people with AIDS. In contrast, the related species C. gattii is …

Just as Koch's postulates formed the foundation of early infectious disease study, Stanley
Falkow's molecular Koch's postulates define best practice in determining whether a specific …

Cryptococcus neoformans is a ubiquitous human fungal pathogen that causes
meningoencephalitis in predominantly immunocompromised hosts. The fungus is typically …

Improper disposal practices have caused environmental disruptions, possessing by heavy
metal ions and radioactive elements in water and soil, where the innovative and sustainable …

Calcineurin governs stress survival, sexual differentiation, and virulence of the human fungal
pathogen Cryptococcus neoformans. Calcineurin is activated by increased Ca2+ levels …

The study of regulatory networks in human pathogens such as Cryptococcus neoformans
provides insights into host-pathogen interactions that may allow for correlation of gene …