Heart failure in diabetes
Heart failure and cardiovascular disorders represent the leading cause of death in diabetic
patients. Here we present a systematic review of the main mechanisms underlying the …
patients. Here we present a systematic review of the main mechanisms underlying the …
[HTML][HTML] Glycemic control and the heart: the tale of diabetic cardiomyopathy continues
M Longo, L Scappaticcio, P Cirillo, A Maio… - Biomolecules, 2022 - mdpi.com
Cardiovascular diseases are the leading cause of death in people with diabetes. Diabetic
cardiomyopathy (DC) is an important complication of diabetes and represents a distinct …
cardiomyopathy (DC) is an important complication of diabetes and represents a distinct …
[HTML][HTML] The ameliorative effect of zinc acetate with caffeic acid in the animal model of type 2 diabetes
Recently the complexation-mediated antioxidative and glycaemic control synergism
between zinc (II) and caffeic acid was demonstrated in vitro. The present study evaluated the …
between zinc (II) and caffeic acid was demonstrated in vitro. The present study evaluated the …
[HTML][HTML] Inhibition of pyruvate dehydrogenase in the heart as an initiating event in the development of diabetic cardiomyopathy
Obesity affects a growing fraction of the population and is a risk factor for type 2 diabetes
and cardiovascular disease. Even in the absence of hypertension and coronary artery …
and cardiovascular disease. Even in the absence of hypertension and coronary artery …
Stimulating cardiac glucose oxidation lessens the severity of heart failure in aged female mice
Heart failure is a prevalent disease worldwide. While it is well accepted that heart failure
involves changes in myocardial energetics, what alterations that occur in fatty acid oxidation …
involves changes in myocardial energetics, what alterations that occur in fatty acid oxidation …
The Arylamine N-Acetyltransferases as Therapeutic Targets in Metabolic Diseases Associated with Mitochondrial Dysfunction
C Choudhury, MK Gill, CE McAleese, NJ Butcher… - Pharmacological …, 2024 - ASPET
In humans, there are two arylamine N-acetyltransferase genes that encode functional
enzymes (NAT1 and NAT2) as well as one pseudogene, all of which are located together on …
enzymes (NAT1 and NAT2) as well as one pseudogene, all of which are located together on …
[HTML][HTML] Energy metabolism homeostasis in cardiovascular diseases
W Lu-Yun, C Chen - Journal of Geriatric Cardiology: JGC, 2021 - ncbi.nlm.nih.gov
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the general
population. Energy metabolism disturbance is one of the early abnormalities in CVDs, such …
population. Energy metabolism disturbance is one of the early abnormalities in CVDs, such …
Effects of hypoxia in cardiac metabolic remodeling and heart failure
M Jiang, X Fan, Y Wang, X Sun - Experimental Cell Research, 2023 - Elsevier
Aerobic cellular respiration requires oxygen, which is an essential part of cardiomyocyte
metabolism. Thus, oxygen is required for the physiologic metabolic activities and …
metabolism. Thus, oxygen is required for the physiologic metabolic activities and …
[HTML][HTML] Ketone Bodies after Cardiac Arrest: A Narrative Review and the Rationale for Use
Cardiac arrest survivors suffer the repercussions of anoxic brain injury, a critical factor
influencing long-term prognosis. This injury is characterised by profound and enduring …
influencing long-term prognosis. This injury is characterised by profound and enduring …
[HTML][HTML] Reciprocal Regulation of Cardiac β-Oxidation and Pyruvate Dehydrogenase by Insulin
The heart alters the rate and relative oxidation of fatty acids and glucose based on
availability and energetic demand. Insulin plays a crucial role in this process diminishing …
availability and energetic demand. Insulin plays a crucial role in this process diminishing …