[HTML][HTML] Pharmacogenomics and the Yin/Yang actions of ginseng: anti-tumor, angiomodulating and steroid-like activities of ginsenosides

PYK Yue, NK Mak, YK Cheng, KW Leung, TB Ng… - Chinese medicine, 2007 - Springer
Abstract In Chinese medicine, ginseng (Panax ginseng CA Meyer) has long been used as a
general tonic or an adaptogen to promote longevity and enhance bodily functions. It has …

Upregulation of vascular endothelial growth factor by H2O2 in rat heart endothelial cells

CC Chua, RC Hamdy, BHL Chua - Free Radical Biology and Medicine, 1998 - Elsevier
Hydrogen peroxide (H2O2) is a reactive oxygen species generated by several metabolic
pathways in mammalian cells. Endothelial cells are extremely susceptible to oxidative …

Hyperoxic injury decreases alveolar epithelial cell expression of vascular endothelial growth factor (VEGF) in neonatal rabbit lung.

WM Maniscalco, RH Watkins, CT D'Angio… - American journal of …, 1997 - atsjournals.org
Normal neonatal lung growth requires a substantial increase in microvascular endothelial
cells. Oxygen injury to neonatal lung destroys endothelial cells and alters the normal …

Hypoxia‐mediated stimulation of carcinoma cell invasiveness via upregulation of urokinase receptor expression

CH Graham, J Forsdike, CJ Fitzgerald… - … journal of cancer, 1999 - Wiley Online Library
Tumor hypoxia and high levels of expression of the urokinase‐type plasminogen activator
(uPA) receptor (uPAR) represent a poor clinical outcome for patients with various cancers …

[HTML][HTML] On the mechanism of thrombin-induced angiogenesis: potentiation of vascular endothelial growth factor activity on endothelial cells by up-regulation of its …

NE Tsopanoglou, ME Maragoudakis - Journal of Biological Chemistry, 1999 - ASBMB
Many of the cellular actions of thrombin may contribute to the angiogenesis-promoting effect
of thrombin reported previously. In this study, we investigated the interaction between …

Experimental diabetes causes breakdown of the blood-retina barrier by a mechanism involving tyrosine nitration and increases in expression of vascular endothelial …

AB El-Remessy, MA Behzadian… - The American journal of …, 2003 - Elsevier
The purpose of these experiments was to determine the specific role of reactive oxygen
species (ROS) in the blood-retinal barrier (BRB) breakdown that characterizes the early …

[HTML][HTML] Could vitamin D be effective in prevention of preeclampsia?

E Poniedziałek-Czajkowska, R Mierzyński - Nutrients, 2021 - mdpi.com
Prevention of preeclampsia (PE) remains one of the most significant problems in perinatal
medicine. Due to the possible unpredictable course of hypertension in pregnancy, primarily …

Regulation of VEGF/VPF expression in tumor cells: consequences for tumor growth and metastasis

KP Claffey, GS Robinson - Cancer and Metastasis Reviews, 1996 - Springer
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF)
is a multifunctional cytokine which potently stimulates angiogenesis in vivo. VEGF/VPF …

Urokinase‐type plasminogen activator expression correlates with tumor angiogenesis and poor outcome in gastric cancer

T Kaneko, H Konno, M Baba, T Tanaka… - Cancer …, 2003 - Wiley Online Library
Urokinase plasminogen activating system (PA system) and vascular endothelial growth
factor (VEGF) were recently suggested to contribute synergistically to tumor progression. To …

Urokinase receptor antagonists inhibit angiogenesis and primary tumor growth in syngeneic mice

HY Min, LV Doyle, CR Vitt, CL Zandonella… - Cancer Research, 1996 - AACR
Urokinase plasminogen activator (uPA) and its receptor are key components of a cell
surface proteolytic cascade used by tumor cells and capillary endothelial cells for basement …