Recent advances in nanoformulations for quercetin delivery

EM Tomou, P Papakyriakopoulou, EM Saitani… - Pharmaceutics, 2023 - mdpi.com
Quercetin (QUE) is a flavonol that has recently received great attention from the research
community due to its important pharmacological properties. However, QUE's low solubility …

Synthetic pathways and the therapeutic potential of quercetin and curcumin

AA Hasan, V Tatarskiy, E Kalinina - International Journal of Molecular …, 2022 - mdpi.com
Polyphenols are considered popular ingredients in the pharmaceutical and medical fields
due to their preventive and therapeutic properties. However, the potential effects and …

Anticancer mechanism of flavonoids on high-grade adult-type diffuse gliomas

SC Wong, MNA Kamarudin, R Naidu - Nutrients, 2023 - mdpi.com
High-grade adult-type diffuse gliomas are the most common and deadliest malignant adult
tumors of the central nervous system. Despite the advancements in the multimodality …

Anticancer and apoptosis inducing potential of quercetin against a wide range of human malignancies

M Shahbaz, H Naeem, U Momal, M Imran… - … Journal of Food …, 2023 - Taylor & Francis
Quercetin, a flavonoid, is a dietary component that has attracted the attention of dietitians
and medicinal chemists due to its anticancer potential. It is an antioxidant that has a …

Nanoformulations of quercetin for controlled delivery: A review of preclinical anticancer studies

H Joshi, DS Gupta, G Kaur, T Singh… - Naunyn-Schmiedeberg's …, 2023 - Springer
One of the well-studied older molecules, quercetin, is found in large quantities in many fruits
and vegetables. Natural anti-oxidant quercetin has demonstrated numerous …

Recent insights into nanoformulation delivery systems of flavonoids against glioblastoma

A Alshweiat, M Jaber, T Athamneh, M Oqal - Journal of Drug Delivery …, 2023 - Elsevier
Glioblastoma (GBM) is the most aggressive brain tumor. Despite the intensive treatment and
interventions, the median survival of GBM patients remains short. The complex molecular …

Functionalized nanoparticles crossing the brain–blood barrier to target glioma cells

Y Wu, Y Qian, W Peng, X Qi - PeerJ, 2023 - peerj.com
Glioma is the most common tumor of the central nervous system (CNS), with a 5-year
survival rate of< 35%. Drug therapy, such as chemotherapeutic and immunotherapeutic …

The development of nanocarriers for natural products

L Huang, S Luo, S Tong, Z Lv… - Wiley Interdisciplinary …, 2024 - Wiley Online Library
Natural bioactive compounds from plants exhibit substantial pharmacological potency and
therapeutic value. However, the development of most plant bioactive compounds is …

Optimization and characterization of quercetin-loaded solid lipid nanoparticles for biomedical application in colorectal cancer

JMM Mohamed, F Ahmad, M El-Sherbiny… - Cancer …, 2024 - Springer
Background Colorectal cancer (CRC) is a type of cancer that affects the colon or rectum and
occurs in individuals over the age of 50, although it can affect people of all ages. Quercetin …

2-Aminothiazole-Flavonoid Hybrid Derivatives Binding to Tau Protein and Responsible for Antitumor Activity in Glioblastoma

R Hedna, A DiMaio, M Robin, D Allegro… - International Journal of …, 2023 - mdpi.com
Tau protein has been described for several decades as a promoter of tubulin assembly into
microtubules. Dysregulation or alterations in Tau expression have been related to various …