Lymphoid cells play a critical role in the immune system, which includes three subgroups of
T, B, and NK cells. Recognition of the complexity of the human genetics transcriptome in …

The most frequent chromosomal rearrangement in childhood B-cell acute lymphoblastic
leukemia (B-ALL) is translocation t (12; 21)(p13; q22). It results in the fusion of the ETV6 …

Caralluma europaea (Guss.) is an important medicinal plant widely used in Morocco for
various traditional purposes. Our work aimed to evaluate the phenolic composition, wound …

The functional relevance of K+ and Ca2+ ion channels in the “Store Operated Calcium
Entry”(SOCE) during B and T lymphocyte activation is well proven. However, their role in the …

Recent years have brought significant progress in the treatment of B-cell acute
lymphoblastic leukemia (ALL). This was influenced by both the improved schemes of …

Abstract IKZF1 (IKAROS family Zinc Finger 1) alteration is an essential regulator of both T-
and B-cell lineage specification with leukemogenic potential. IKZF1 deletion have been …

Introduction: Acute lymphoblastic leukemia (ALL) is a prevalent childhood cancer with high
cure rate, but poses a significant medical challenge in adults and relapsed patients …

Acute lymphoblastic leukemia (ALL) is a common cancer affecting children worldwide. The
development of ALL is driven by several genes, some of which can be targeted for treatment …

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Current
chemotherapy treatment regimens have improved survival rates to approximately 80%; …

B-cell lymphoblastic leukemia is a hematologic neoplasm that poses a serious health
concern in childhood. Genetic aberrations, such as mutations in the genes IL-7, IL7R, JAK1 …