The important role of GH in the control of mammalian longevity was first deduced from
extended longevity of mice with genetic GH deficiency (GHD) or GH resistance. Mice with …

Aging research has experienced a burst of scientific efforts in the last decades as the
growing ratio of elderly people has begun to pose an increased burden on the healthcare …

The association between IGF‐1 levels and mortality in humans is complex with low levels
being associated with both low and high mortality. The present meta‐analysis investigates …

While the lifespan advantage of small body size and mixed breed status has been
documented repeatedly, evidence for an effect of genetic diversity across dog breeds is …

The twofold life expectancy difference between dog breeds predicts differential behavioral
and cognitive aging patterns between short-and long-lived dogs. To investigate this …

Cancer is a leading cause of death in domestic dogs. Deaths due to cancer vary widely
among breeds, providing an opportunity for testing the multi-stage model of carcinogenesis …

Background Lipomas are masses of mesenchymal origin, comprising of adipocytes, and are
often clinically unremarkable but can be alarming to owners. Although lipomas are …

The life expectancy provides valuable information about population health. The life
expectancies were evaluated in 12,039 dogs which were buried or cremated during January …

Aging is the single most important cause of disease, disability, and death in adult dogs.
Contrary to the common view of aging as a mysterious and inevitable natural event, it is …

Dogs are exceptionally well adapted to life close to humans, and alterations in their
endocrine system during the domestication process may be an underlying mechanism. In …