Avibactam is a non-β-lactam, β-lactamase inhibitor of the diazabicyclooctane class that
covalently acylates its β-lactamase targets, encompassing extended spectrum of activities …

Background: Complicated urinary tract infections (cUTI) are universal reasons for
hospitalization, and highly likely to develop into sepsis or septic shock. Carbapenem …

This study characterized the β-lactamase content of baseline pathogens recovered from
patients with complicated urinary tract infections (cUTI), including acute pyelonephritis, who …

Objective To compare the efficacy and safety of short-course intravenous levofloxacin
(LVFX) 750 mg with a conventional intravenous/oral regimen of LVFX 500 mg in patients …

Introduction Complicated urinary tract infections (cUTIs) are associated with poor prognosis.
The widespread infection of multidrug-resistant Gram-negative uropathogens such as …

Purpose The goal of this study was to examine treatment patterns, utilization, and costs for
complicated urinary tract infections (UTIs) requiring inpatient/emergency department (ED) …

This systematic review and meta-analysis evaluated the clinical efficacy and safety of
carbapenems for the treatment of complicated urinary tract infections (cUTIs), with the …

Objective To evaluate whether stopping the effective antibiotic treatment following clinical
improvement at Day 7 (Truncated treatment) would be non-inferior to continued treatment …

Background Specific data concerning the efficacy of alternative antibiotics for carbapenems
against complicated urinary tract infections (cUTIs) attributed to antimicrobial-resistant …

Objectives Active-comparator, non-inferiority study designs are used in uncomplicated
urinary tract infection (uUTI) to establish the efficacy of a new antibacterial, given the …