CaMKII as a therapeutic target in cardiovascular disease

OE Reyes Gaido, LJ Nkashama… - Annual review of …, 2023 - annualreviews.org
CaMKII (the multifunctional Ca2+ and calmodulin-dependent protein kinase II) is a highly
validated signal for promoting a variety of common diseases, particularly in the …

Advances and challenges in cell biology for cultured meat

B Martins, A Bister, RGJ Dohmen… - Annual review of …, 2024 - annualreviews.org
Cultured meat is an emerging biotechnology that aims to produce meat from animal cell
culture, rather than from the raising and slaughtering of livestock, on environmental and …

Regulation of the myoblast fusion reaction for muscle development, regeneration, and adaptations

DP Millay - Experimental cell research, 2022 - Elsevier
Fusion of plasma membranes is essential for skeletal muscle development, regeneration,
exercise-induced adaptations, and results in a cell that contains hundreds to thousands of …

[HTML][HTML] Satellite cells sourced from bull calves and dairy cows differs in proliferative and myogenic capacity–implications for cultivated meat

S Skrivergaard, MK Rasmussen… - Food Research …, 2023 - Elsevier
Cultivated meat produced with primary muscle satellite cells (SCs) will need a continuous
supply of isolated cell material from relevant animal donors. Factors such as age, sex, and …

Molecular mechanisms underlying the impact of muscle fiber types on meat quality in livestock and poultry

M Mo, Z Zhang, X Wang, W Shen, L Zhang… - Frontiers in Veterinary …, 2023 - frontiersin.org
In the past, the primary emphasis of livestock and poultry breeding was mainly on improving
the growth rate, meat production efficiency and disease resistance. However, the …

Ageing of skeletal muscle extracellular matrix and mitochondria: finding a potential link

L Cai, L Shi, Z Peng, Y Sun, J Chen - Annals of Medicine, 2023 - Taylor & Francis
Aim: To discuss the progress of extracellular matrix (ECM) characteristics, mitochondrial
homeostasis, and their potential crosstalk in the pathogenesis of sarcopenia, a geriatric …

Continuous fish muscle cell line with capacity for myogenic and adipogenic-like phenotypes

MK Saad, JSK Yuen Jr, CM Joyce, X Li, T Lim… - Scientific Reports, 2023 - nature.com
Cell-cultivated fish offers the potential for a more ethical, sustainable, and safe seafood
system. However, fish cell culture is relatively understudied in comparison to mammalian …

Carbon dioxide regulates cholesterol levels through SREBP2

N Bolshette, S Ezagouri, V Dandavate, I Karavaeva… - PLoS …, 2023 - journals.plos.org
In mammals, O2 and CO2 levels are tightly regulated and are altered under various
pathological conditions. While the molecular mechanisms that participate in O2 sensing are …

Fibroblast growth factor 8b (FGF-8b) enhances myogenesis and inhibits adipogenesis in rotator cuff muscle cell populations in vitro

T Otsuka, HM Kan, PY Mengsteab… - Proceedings of the …, 2024 - National Acad Sciences
Fatty expansion is one of the features of muscle degeneration due to muscle injuries, and its
presence interferes with muscle regeneration. Specifically, poor clinical outcomes have …

Neuronal agrin promotes proliferation of primary human myoblasts in an age-dependent manner

K Gros, U Matkovič, G Parato, K Miš, E Luin… - International Journal of …, 2022 - mdpi.com
Neuronal agrin, a heparan sulphate proteoglycan secreted by the α-motor neurons,
promotes the formation and maintenance of the neuromuscular junction by binding to Lrp4 …