Infertility is a major global health issue and male factors account for half of all infertility
cases. One of the causes of male infertility is the loss of spermatogonial stem cells, which …

Substantial improvements in cancer treatment have resulted in longer survival and
increased quality of life in cancer survivors with minimized long-term toxicity. However …

AIMS: The aims of this study were to evaluate the germinal cells characteristics and repairs
in seminiferous tubules of busulfan-induced azoospermic rats after AT-MSCs …

Background Busulfan is an antineoplastic medication that is broadly utilized for cancer
treatment. It affects the testicular function and leads to sterility. The present study aimed to …

BACKGROUND Although the prognosis of childhood cancer survivors has increased
dramatically during recent years, chemotherapy and radiation treatments for cancer and …

Background Busulfan (BU) has a destructive effect on the male reproductive system. The
goal of this study was to assess the effects of olive leaf extract (OLE) as a source of …

In this study, we determined the effects of hederagenin isolated from Akebia quinata fruit on
alcohol-induced hepatotoxicity in rats. Specifically, we investigated the hepatoprotective …

Background: Mesenchymal stem cells (MSCs) are undifferentiated cells that can differentiate
and divide to other cell types. Transplantation of these cells to the different organs is used for …

Busulfan is a widely used chemotherapeutic drug for chronic myelogenous leukemia and
bone marrow transplantation. As a cell cycle nonspecific alkylation agent, busulfan has a …

The aim of the present study was stereological evaluation of testes of azoospermic animal
model using busulfan in rat. Three groups of male adult rats were used in this study. The first …