Response of mesenchymal stem cells to surface topography of scaffolds and the underlying mechanisms

L Xiao, Y Sun, L Liao, X Su - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Mesenchymal stem/stromal cells (MSCs) serve as essential components of regenerative
medicine. Their destiny is influenced by the interaction of the cells with the external …

[HTML][HTML] Replication of natural surface topographies to generate advanced cell culture substrates

NO Monteiro, JF Fangueiro, RL Reis, NM Neves - Bioactive Materials, 2023 - Elsevier
Surface topographies of cell culture substrates can be used to generate in vitro cell culture
environments similar to the in vivo cell niches. In vivo, the physical properties of the …

Effect of simultaneous and sequential use of TGF-β1 and TGF-β3 with FGF-2 on teno/ligamentogenic differentiation of periodontal ligament stem cells

F Atarbashi-Moghadam, A Azadi… - Archives of Oral …, 2024 - Elsevier
Objective The periodontal ligament is a crucial part of the periodontium, and its regeneration
is challenging. This study compares the effect of simultaneous and sequential use of FGF-2 …

Differential Smad2/3 linker phosphorylation is a crosstalk mechanism of Rho/ROCK and canonical TGF-β3 signaling in tenogenic differentiation

M Melzer, S Niebert, M Heimann, F Ullm, T Pompe… - Scientific Reports, 2024 - nature.com
The transforming growth factor (TGF)-β3 is a well-known inducer for tenogenic
differentiation, signaling via the Smad2/3 pathway. Furthermore, other factors like …

MSC in tendon and joint disease: The context-sensitive link between targets and therapeutic mechanisms

SP Roth, J Burk, W Brehm, A Troillet - Frontiers in bioengineering and …, 2022 - frontiersin.org
Mesenchymal stromal cells (MSC) represent a promising treatment option for tendon
disorders and joint diseases, primarily osteoarthritis. Since MSC are highly context-sensitive …

The biomimetic surface topography of Rubus fruticosus leaves stimulate the induction of osteogenic differentiation of rBMSCs

NO Monteiro, MR Casanova, JF Fangueiro… - Biomedical …, 2023 - iopscience.iop.org
The interaction between cells and biomaterials is essential for the success of biomedical
applications in which the implantation of biomaterials in the human body is necessary. It has …

Influence of Rho/ROCK inhibitor Y-27632 on proliferation of equine mesenchymal stromal cells

M Melzer, J Burk, DJ Guest, J Dudhia - Frontiers in Veterinary Science, 2023 - frontiersin.org
Mesenchymal stromal cells (MSC) isolated form bone marrow and adipose tissue are the
most common cells used for cell therapy of orthopedic diseases. MSC derived from different …

Mechanistic study on ursolic acid inhibiting the growth of colorectal cancer cells through the downregulation of TGF‐β3 by miR‐140‐5p

T Zhang, F Xiang, X Li, Z Chen, J Wang… - … of Biochemical and …, 2024 - Wiley Online Library
Colorectal cancer (CRC) is a common digestive tract tumor with a high incidence and a poor
prognosis. Traditional chemotherapy drugs are usually accompanied by unpleasant side …

[HTML][HTML] 不同细胞因子对诱导间充质干细胞在肌腱损伤修复中的研究进展

李万祥, 苑龙, 李森, 延易泽, 卞继超… - Advances in Clinical …, 2022 - hanspub.org
肌腱的损伤在运动和工作场所很常见, 它与体育活动, 反复微创伤, 抑制机制功能障碍,
退行性改变以及全身或局部皮质类固醇治疗有关, 每年全世界数千万人受到影响 …

OPEN ACCESS EDITED BY Eleonora lacono, University of Bologna, Italy

JU Carmona, A Lange-Consiglio, J Burk… - Rising Stars in …, 2023 - books.google.com
Platelets play a crucial role in hemostasis and contain various cytokines, chemokines and
growth factors, which are released after activation (1). These messenger substances cause …