A myriad of physiological processes in mammals are influenced by estrogens and the
estrogen receptors (ERs), ERα and ERβ. As we reviewed previously, given the widespread …

The use of immunohistochemistry (IHC) in clinical cohorts is of paramount importance in
determining the utility of a biomarker in clinical practice. A major bottleneck in translating a …

Background There is a well established link between obesity and cancer. Emerging
research is characterising this relationship further and delineating the specific role of excess …

Background Investigating the expression of candidate genes in tissue samples usually
involves either immunohistochemical labelling of formalin-fixed paraffin-embedded (FFPE) …

Fibroblast activation protein (FAP), a selective protein for tumor stromal fibroblasts, is
expressed in> 90% of human epithelial carcinomas. A characteristic feature of pancreatic …

Numerous epidemiologic studies demonstrate an association between obesity, insulin
resistance, hyperinsulinemia, and the development of cancer at several sites …

背景: 甲醛固定石蜡包埋的标本易于保存, 免疫荧光法定位定量能精确支持多种标记物. 目的:
建立适合于甲醛固定石蜡包埋组织的改良免疫荧光法. 方法: 将取自类风湿性关节炎和无骨性 …

OBJECTIVES: To investigate fasting glucose, glucose tolerance, INSULIN RESISTANCE
and insulin–like growth factor 1 in patients with or without COLORECTAL POLYPS …

Background: The principal objective of the present study was to examine the association of
insulin resistance and glycated hemoglobin level with the presenceofcolorectal polyps in …

BACKGROUND: Formalin fixed paraffin embedded tissue (FFPE) is apt for storage, and
immunofluorescence method supports precise localization and quantitation as well as …