New antibiotics for multidrug-resistant bacterial strains: latest research developments and future perspectives

M Terreni, M Taccani, M Pregnolato - Molecules, 2021 - mdpi.com
The present work aims to examine the worrying problem of antibiotic resistance and the
emergence of multidrug-resistant bacterial strains, which have now become really common …

[HTML][HTML] Solid lipid nanoparticles for drug delivery: pharmacological and biopharmaceutical aspects

S Scioli Montoto, G Muraca, ME Ruiz - Frontiers in molecular …, 2020 - frontiersin.org
In the golden age of pharmaceutical nanocarriers, we are witnessing a maturation stage of
the original concepts and ideas. There is no doubt that nanoformulations are extremely …

Nanomedicine fight against antibacterial resistance: an overview of the recent pharmaceutical innovations

NE Eleraky, A Allam, SB Hassan, MM Omar - Pharmaceutics, 2020 - mdpi.com
Based on the recent reports of World Health Organization, increased antibiotic resistance
prevalence among bacteria represents the greatest challenge to human health. In addition …

Lipid nanoparticles as delivery vehicles for inhaled therapeutics

EWX Leong, R Ge - Biomedicines, 2022 - mdpi.com
Lipid nanoparticles (LNPs) have emerged as a powerful non-viral carrier for drug delivery.
With the prevalence of respiratory diseases, particularly highlighted by the current COVID-19 …

Inhaled nanoparticles–An updated review

T Praphawatvet, JI Peters, RO Williams III - International journal of …, 2020 - Elsevier
We are providing an update to our previously published review paper on inhaled
nanoparticles, thus updating with the most recent reports in the literature. The field of …

Pulmonary delivery nanomedicines towards circumventing physiological barriers: Strategies and characterization approaches

W Wang, Z Huang, Y Huang, X Zhang, J Huang… - Advanced Drug Delivery …, 2022 - Elsevier
Pulmonary delivery of nanomedicines is very promising in lung local disease treatments
whereas several physiological barriers limit its application via the interaction with inhaled …

Emerging antibacterial nanomedicine for enhanced antibiotic therapy

S Wang, Y Gao, Q Jin, J Ji - Biomaterials Science, 2020 - pubs.rsc.org
Antibiotic therapy is the most powerful strategy for treating bacterial infections in clinic.
However, antibiotic resistance has become one of the biggest threats to public health …

Engineering hybrid nanosystems for efficient and targeted delivery against bacterial infections

E Elhassan, N Devnarain, M Mohammed… - Journal of Controlled …, 2022 - Elsevier
Hybrid nanoparticles (NPs) are emerging as superior alternatives to conventional
nanocarriers for enhancing the delivery of antibiotics and improving their targeting at the …

Cytotoxic Screening and Enhanced Anticancer Activity of Lippia alba and Clinopodium nepeta Essential Oils-Loaded Biocompatible Lipid Nanoparticles against Lung …

B Rodenak-Kladniew, MA Castro, RC Gambaro… - Pharmaceutics, 2023 - mdpi.com
Plant and herbal essential oils (EOs) offer a wide range of pharmacological actions that
include anticancer effects. Here, we evaluated the cytotoxic activity of EO from Lippia alba …

Nanotechnology based therapeutic approaches: An advanced strategy to target the biofilm of ESKAPE pathogens

A Mukherjee, S Bose, A Shaoo, SK Das - Materials Advances, 2023 - pubs.rsc.org
Bacterial infection by ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella
pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Enterobacter spp.) …