Sustained release glaucoma therapies: Novel modalities for overcoming key treatment barriers associated with topical medications

A Belamkar, A Harris, R Zukerman, B Siesky… - Annals of …, 2022 - Taylor & Francis
Glaucoma is a progressive optic neuropathy and a leading cause of irreversible blindness.
The disease has conventionally been characterized by an elevated intraocular pressure …

Recent advancements in nanomaterial-laden contact lenses for diagnosis and treatment of glaucoma, review and update

R Baghban, MR Talebnejad, A Meshksar… - Journal of …, 2023 - Springer
Despite the existence of numerous eye drops in the market, most of them are not sufficiently
effective because of quick clearance and the barriers within the eye. To increase the delivery …

Wireless theranostic smart contact lens for monitoring and control of intraocular pressure in glaucoma

TY Kim, JW Mok, SH Hong, SH Jeong, H Choi… - Nature …, 2022 - nature.com
Glaucoma is one of the irreversible ocular diseases that can cause vision loss in some
serious cases. Although Triggerfish has been commercialized for monitoring intraocular …

Co-delivery of latanoprost and timolol from micelles-laden contact lenses for the treatment of glaucoma

J Xu, Y Ge, R Bu, A Zhang, S Feng, J Wang… - Journal of controlled …, 2019 - Elsevier
Glaucoma is a group of irreversible ocular diseases which result in damage to the optic
nerve and vision loss. The objective of the present work was to develop micelles-laden …

[PDF][PDF] Current management of glaucoma and the need for complete therapy

SJ McKinnon, LD Goldberg, P Peeples, JG Walt… - Am J Manag Care, 2008 - aoa.org
Glaucoma is a long-term ocular neuropathy defined by optic disc or retinal nerve fiber
structural abnormalities and visual field abnormality. Primary open-angle glaucoma is the …

Micelles: Promising ocular drug carriers for anterior and posterior segment diseases

ME Durgun, S Güngör, Y Özsoy - Journal of Ocular Pharmacology …, 2020 - liebertpub.com
Micelles have been studied in the targeting of drug substances to different tissues as a nano-
sized delivery system for many years. Sustained drug release, ease of production, increased …

Bioinspired imprinted PHEMA-hydrogels for ocular delivery of carbonic anhydrase inhibitor drugs

A Ribeiro, F Veiga, D Santos… - …, 2011 - ACS Publications
Hydrogels with high affinity for carbonic anhydrase (CA) inhibitor drugs have been designed
trying to mimic the active site of the physiological metallo-enzyme receptor. Using …

Serum cytokine alteration is associated with optic neuropathy in human primary open angle glaucoma

P Huang, Y Qi, YS Xu, J Liu, D Liao… - Journal of …, 2010 - journals.lww.com
Purpose The purpose of this study is to compare human serum levels of TH 1 and TH 2
cytokines between 2 stages of primary open-angle glaucoma (POAG) and nonglaucomatous …

Medication adherence in glaucoma: approaches for optimizing patient compliance

JC Tsai - Current opinion in ophthalmology, 2006 - journals.lww.com
Many factors are associated with the lack of medication adherence in patients. The solution
is likely to be multi-dimensional and employ combination strategy (must be individualized for …

Glaucoma: present challenges and future trends

P Bettin, F Di Matteo - Ophthalmic research, 2013 - karger.com
The authors indicate four key issues which, in their opinion, represent the most stimulating
challenges in the field of glaucoma today, and describe the present approaches and the …